Journal ArticleDOI
Infectious disease : antenatal interventions against sexually transmitted disease in Africa
TLDR
Zambia's pilot project suggests that mandatory prenatal screening for syphilis could usher in other prenatal interventions against STDs an research into the effectiveness of prenatal care and maternal health.About:
This article is published in The Lancet.The article was published on 1993-06-19. It has received 8 citations till now. The article focuses on the topics: Prenatal care & Sexually transmitted disease.read more
Citations
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Journal ArticleDOI
Longevity Complementarities Under Competing Risks
TL;DR: Dow et al. as discussed by the authors argued that there are inherent complementarities between investments in the prevention of cause-specific mortality risks, both on the individual level and on the aggregate level.
Journal Article
Risk assessment and other screening options for gonorrhoea and chlamydial infections in women attending rural Tanzanian antenatal clinics.
Philippe Mayaud,Heiner Grosskurth,J Changalucha,Jim Todd,Beryl West,R. Gabone,Kesheni P. Senkoro,Mary Rusizoka,Marie Laga,Richard J. Hayes +9 more
TL;DR: A risk score approach that was developed, based on sociodemographic and other factors associated with NG/CT infection, had a higher sensitivity and lower cost per true case treated than other approaches, although its positive predictive value was only about 20%.
Journal ArticleDOI
T-cell responses to the components of pyruvate dehydrogenase complex in primary biliary cirrhosis
David Jones,Jeremy M. Palmer,Oliver F. W. James,Stephen J. Yeaman,Margaret F. Bassendine,A. G. Diamond +5 more
TL;DR: The authors have characterized the peripheral blood T‐cell proliferative responses of 24 PBC patients and 48 controls to the dominant autoantigen PDC, and its constituent components E1, E2 and protein X (which co‐purify), and E3, and found that peripheral mechanisms may play a significant role in maintaining self‐tolerance to PDC in the normal state.
Journal ArticleDOI
Novel potent 5-HT(1F) receptor agonists: structure-activity studies of a series of substituted N-[3-(1-methyl-4-piperidinyl)-1H-pyrrolo[3,2-b]pyridin-5-yl]amides.
Sandra Ann Filla,Brian Michael Mathes,Kirk W. Johnson,Lee A. Phebus,Marlene L. Cohen,David L. Nelson,John M. Zgombick,Jon A. Erickson,Kathryn W. Schenck,David B. Wainscott,Theresa A Branchek,John Mehnert Schaus +11 more
TL;DR: These SAR studies identified SSOFRAs that demonstrated oral activity in the neurogenic plasma protein extravasation model, a model indicative of antimigraine activity.
Journal Article
Screening for sexually transmitted diseases in rural women in Papua New Guinea: are WHO therapeutic algorithms appropriate for case detection?
TL;DR: Data from a community-based study of STDs is used to develop and evaluate algorithms for detection of cervical infection with Chlamydia trachomatis or Neisseria gonorrhoeae, and for Detection of vaginal infection with Trichomonas vaginalis or bacterial vaginosis.
References
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Journal ArticleDOI
A randomized placebo-controlled trial of erythromycin for the treatment of Ureaplasma urealyticum to prevent premature delivery
David A. Eschenbach,Robert P. Nugent,A. Vijaya Rao,Mary Frances Cotch,Ronald S. Gibbs,Kathleen A. Lipscomb,David H. Martin,Joseph G. Pastorek,Philip J. Rettig,J. Christopher Carey,Joan A. Regan,Kim L. Geromanos,Molly L.F. Lee,W. Kenneth Poole,Robert R. Edelman +14 more
TL;DR: There were no significant differences between erythromycin- and placebo-treated women in infant birth weight or gestational age at delivery, in frequency of premature rupture of membranes, or in neonatal outcome.
Journal ArticleDOI
Adjunctive erythromycin treatment for idiopathic preterm labor: results of a randomized, double-blinded, placebo-controlled trial.
TL;DR: Adjunctive erythromycin given to women treated for preterm labor less than or equal to 34 weeks is associated with prolongation of pregnancy and delivery at 37 weeks only in women with cervical dilatation at the beginning of treatment.
Journal ArticleDOI
Maternal Gonococcal Infection as a Preventable Risk Factor for Low Birth Weight
Beverly Elliott,Robert C. Brunham,Marie Laga,Peter Piot,Jackoniah O. Ndinya-Achola,Gregory Maitha,Mary Cheang,Francis A. Plummer +7 more
TL;DR: Gonococcal infection appears to be responsible for a substantial proportion of premature births and is theoretically preventable by antenatal case detection and treatment.