Journal ArticleDOI
Injectable antibacterial conductive hydrogels with dual response to an electric field and pH for localized “smart” drug release
TLDR
A series of injectable conductive hydrogels based on chitosan-graft-polyaniline (CP) copolymer and oxidized dextran (OD) with "smart" delivery vehicles with electro-responsiveness and pH-responsive properties for triggered and localized release of drugs are designed.About:
This article is published in Acta Biomaterialia.The article was published on 2018-05-01. It has received 299 citations till now. The article focuses on the topics: Self-healing hydrogels & Drug carrier.read more
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Antibacterial adhesive injectable hydrogels with rapid self-healing, extensibility and compressibility as wound dressing for joints skin wound healing.
TL;DR: In vivo experiments indicated that curcumin loaded hydrogels significantly accelerated wound healing rate with higher granulation tissue thickness and collagen disposition and upregulated vascular endothelial growth factor (VEGF) in a full-thickness skin defect model.
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Adhesive Hemostatic Conducting Injectable Composite Hydrogels with Sustained Drug Release and Photothermal Antibacterial Activity to Promote Full-Thickness Skin Regeneration During Wound Healing
TL;DR: These adhesive hemostatic antioxidant conductive photothermal antibacterial hydrogels based on hyaluronic acid-graft-dopamine and reduced graphene oxide using a H2 O2 /HPR (horseradish peroxidase) system are prepared for wound dressing and are an excellent wound dressing for full-thickness skin repair.
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Functional Hydrogels as Wound Dressing to Enhance Wound Healing.
TL;DR: In this paper, a comprehensive review of the functional hydrogel as a wound dressing is presented, which summarizes the skin wound healing process and relates evaluation parameters and then reviews the advanced functions of hydrogels such as antimicrobial property, adhesion and hemostasis, anti-inflammatory and anti-oxidation, substance delivery, self-healing, stimulus response, conductivity, and the recently emerged wound monitoring feature.
Journal ArticleDOI
Conducting Polymers for Tissue Engineering
Baolin Guo,Peter X. Ma +1 more
TL;DR: The conductive biomaterials used in tissue engineering including conductive composite films, conductive nanofibers, Conductive hydrogels, and Conductive composite scaffolds fabricated by various methods such as electrospinning, coating, or deposition by in situ polymerization are summarized.
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Degradable conductive injectable hydrogels as novel antibacterial, anti-oxidant wound dressings for wound healing
TL;DR: In vivo experiments indicated that hydrogel with AT addition (OHA-AT/CEC hydrogels) significantly accelerated wound healing rate with higher granulation tissue thickness, collagen disposition and more angiogenesis in a full-thickness skin defect model.
References
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Treatment of infections associated with surgical implants.
TL;DR: This review summarizes the diagnostic challenges and explains the approaches to managing infections that are associated with various devices, including prosthetic heart valves, vascular grafts, pacemakers and defibrillators, and joint prostheses.
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Antibiotics For Emerging Pathogens
TL;DR: The emergence of multidrug resistance among the latest generation of pathogens suggests that the discovery of new scaffolds should be a priority, and promising approaches to scaffold discovery are emerging.
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Hydrogels: from controlled release to pH-responsive drug delivery.
TL;DR: This review highlights the use of hydrogels (a class of polymeric systems) in controlled drug delivery, and their application in stimuli- responsive, especially pH-responsive, drug release.
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Infection in Organ-Transplant Recipients
Jay A. Fishman,Robert H. Rubin +1 more
TL;DR: A primary goal in organ transplantation is the prevention or effective treatment of infection, the most common life-threatening complication of long-term immunosuppressive therapy, and the adverse effects of the antimicrobial drugs used for prophylaxis and therapy are studied.
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Antibacterial anti-oxidant electroactive injectable hydrogel as self-healing wound dressing with hemostasis and adhesiveness for cutaneous wound healing
TL;DR: The antibacterial electroactive injectable hydrogel dressing prolonged the lifespan of dressing relying on self-healing ability and significantly promoted the in vivo wound healing process attributed to its multifunctional properties, meaning that they are excellent candidates for full-thickness skin wound healing.