Journal ArticleDOI
Interaction between Ideal Neutral Nanogels: A Monte Carlo Simulation Study
TLDR
This work has performed explicit coarse-grained Monte Carlo simulations to find out if these models can capture the interactions between overlapping neutral nanogels and the soft-sphere and Hertz potentials.Abstract:
The interaction between nanogels is a central question in the field of soft matter which has been scarcely studied. In fact, effective potentials for nanogels are less advanced than for other colloidal particles. The soft-sphere potential and the Hertz potential are two theoretical formalisms used until now by some authors to quantify forces between nano- and microgels. Accordingly, in this work we have performed explicit coarse-grained Monte Carlo simulations to find out if these models can capture the interactions between overlapping neutral nanogels. To this end, pairs of nanogels with different number of monomers per chain have been simulated, and the corresponding effective interaction potentials have been calculated as a function of the distance between their respective centers of mass. Then, our simulation results have been used to analyze the functional form of the soft-sphere and Hertz potentials. Both are too simple to describe nanogel interactions when these nanoparticles overlap to a significa...read more
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Journal ArticleDOI
Nanogels and Microgels: From Model Colloids to Applications, Recent Developments, and Future Trends
Matthias Karg,Andrij Pich,Andrij Pich,Thomas Hellweg,Todd Hoare,L. Andrew Lyon,Jérôme J. Crassous,Daisuke Suzuki,Rustam A. Gumerov,Rustam A. Gumerov,Stefanie Schneider,Igor I. Potemkin,Igor I. Potemkin,Igor I. Potemkin,Walter Richtering +14 more
TL;DR: An overview of the state-of-the-art, recent developments as well as emerging trends in the field of nano- and microgels is provided.
Journal ArticleDOI
In Silico Synthesis of Microgel Particles
TL;DR: This work proposes a novel methodology to assemble realistic microgel particles in silico by exploiting the self-assembly of a binary mixture composed of tetravalent and bivalent particles under spherical confinement to produce fully bonded networks.
Journal ArticleDOI
Numerical modelling of non-ionic microgels: an overview.
Lorenzo Rovigatti,Nicoletta Gnan,Letizia Tavagnacco,Angel J. Moreno,Angel J. Moreno,Emanuela Zaccarelli +5 more
TL;DR: Numerical models of neutral microgels are reviewed, going from the atomistic to the single-particle level, and the state-of-the-art is described.
Journal ArticleDOI
Hydrogel-Based Drug Delivery Nanosystems for the Treatment of Brain Tumors.
João Basso,Ana Miranda,Sandra C.C. Nunes,Tânia F.G.G. Cova,João Sousa,Carla Vitorino,Alberto A. C. C. Pais +6 more
TL;DR: This review focuses on the application of hydrogel matrices containing nanostructured DDS and Hydrogel nanoparticles as potential and promising strategies for the treatment and diagnosis of glioblastoma and other types of brain cancer.
Journal ArticleDOI
Connecting Elasticity and Effective Interactions of Neutral Microgels: The Validity of the Hertzian Model
TL;DR: In this paper, the authors address the question of whether a direct connection exists between single-particle elastic properties and macroscopic bulk behavior and show that there is no direct connection.
References
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Journal ArticleDOI
Determination of elastic moduli of thin layers of soft material using the atomic force microscope.
TL;DR: It is shown that the use of sharp cantilever tips, which typically induce local strains that far exceed the linear material regime, can be alleviated by using microspheres as probes, and the criteria for their use is established.
Journal ArticleDOI
Temperature sensitive microgel suspensions: Colloidal phase behavior and rheology of soft spheres
H. Senff,Walter Richtering +1 more
TL;DR: In this article, the authors investigated the equilibrium colloidal phase behavior of concentrated dispersions of a temperature sensitive microgel, consisting of poly (N-isopropylacrylamid) (PNiPAM) chemically crosslinked with N,N′ methylenbisacryamid (BIS), and showed that with increasing temperature the microgel particles decrease in size (hydrodynamic radius 142 nm at 10°C and 58 nm at 35°C).
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Adhesion and Mechanical Properties of PNIPAM Microgel Films and Their Potential Use as Switchable Cell Culture Substrates
TL;DR: In this paper, thermal-sponsive poly(N-isopropylacrylamide) (PNIPAM) microgel films are shown to allow controlled detachment of adsorbed cells via temperature stimuli.
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Accurate effective pair potentials for polymer solutions
TL;DR: In this paper, the authors used integral equation techniques from the theory of simple fluids to map nonintersecting self-avoiding walk (SAW) polymer chains onto a fluid of soft particles interacting via an effective pair potential between their centers of mass.
Journal ArticleDOI
Gel swelling theories: the classical formalism and recent approaches
TL;DR: In this paper, the classical theory of polymer/polyelectrolyte gel swelling is reviewed and the application to experimental swelling data (of both gels and microgels) is also reviewed.