Journal ArticleDOI
Is Tracheal Gas Insufflation an Alternative to Extrapulmonary Gas Exchangers in Severe ARDS
TLDR
It is concluded that TGI improves tolerance of limited pressure ventilation by removing CO2, but it may induce changes in lung volumes that are not detected by ventilator measurements.About:
This article is published in Chest.The article was published on 1995-05-01. It has received 37 citations till now. The article focuses on the topics: Mechanical ventilation & Artificial ventilation.read more
Citations
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Journal ArticleDOI
Ventilator-induced lung injury: lessons from experimental studies.
Didier Dreyfuss,Georges Saumon +1 more
TL;DR: This paper presents experimental evidence for Increased Vascular Transmural Pressure Evidence for Alterations in Alveolar–Capillary Permeability Contributions of the Static and Dynamic Lung Volume Components to Ventilator-induced Edema High-volume Lung Edema Low Lung Volume Injury.
Journal ArticleDOI
Evolving concepts in the ventilatory management of acute respiratory distress syndrome
TL;DR: The authors reviewed the basis for concern about traditional ventilatory support in acute respiratory distress syndrome (ARDS) and developed an approach based on current evidence and newer options for management, which may retard the healing of the injured lung.
Journal ArticleDOI
Permissive hypercapnia with and without expiratory washout in patients with severe acute respiratory distress syndrome
Pierre Kalfon,G.S. Umamaheswara Rao,Lluis Gallart,L. Puybasset,Pierre Coriat,Jean-Jacques Rouby +5 more
TL;DR: Expiratory washout is an effective and easy‐to‐use ventilatory modality to reduce PaCO2 and increase pH during permissive hypercapnia, however, it significantly increases airway pressures and lung volume through expiratory flow limitation, reexposing some patients to a risk of lung volutrauma if the extrinsic positive end‐expiratory pressure is not substantially reduced.
Journal ArticleDOI
Continuous tracheal gas insufflation enables a volume reduction strategy in hyaline membrane disease : technical aspects and clinical results
TL;DR: Instrumental dead space wash-out can be used to improve carbon dioxide clearance and be a useful adjunct to conventional ventilation in preterm neonates with respiratory disease, enabling an increase in CO2 clearance or a reduction in ventilatory pressure.
Journal ArticleDOI
Efficacy of tracheal gas insufflation in acute respiratory distress syndrome with permissive hypercapnia.
TL;DR: The data suggest that in patients with ARDS the change in PETCO2 may be helpful in predicting the decrement in PaCO2 during TGI, and the existence of a high VDalv tends to limit its effectiveness.
References
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Journal ArticleDOI
High Inflation Pressure Pulmonary Edema: Respective Effects of High Airway Pressure, High Tidal Volume, and Positive End-expiratory Pressure
TL;DR: To the authors' knowledge, this constitutes the first example of a protective effect of PEEP during permeability edema, which was markedly reduced by PEEP and preserved the normal ultrastructural aspect of the alveolar epithelium.
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Extracorporeal membrane oxygenation in severe acute respiratory failure. A randomized prospective study.
Warren M. Zapol,Michael T. Snider,J. D. Hill,R. J. Fallat,Robert H. Bartlett,L. H. Edmunds,A. H. Morris,E C Peirce nd,A. N. Thomas,H. J. Proctor,P. A. Drinker,P. C. Pratt,A. Bagniewski,R. G. Miller +13 more
TL;DR: It is concluded that ECMO can support respiratory gas exchange but did not increase the probability of long-term survival in patients with severe ARF.
Journal ArticleDOI
Low mortality associated with low volume pressure limited ventilation with permissive hypercapnia in severe adult respiratory distress syndrome
TL;DR: In this paper, the authors have shown that ventilator management may substantially reduce mortality in ARDS, particularly from respiratory failure, and suggest that this ventilatory management may significantly reduce mortality.
Journal ArticleDOI
Low-frequency positive-pressure ventilation with extracorporeal CO2 removal in severe acute respiratory failure.
Luciano Gattinoni,Antonio Pesenti,D. Mascheroni,R. Marcolin,Roberto Fumagalli,Francesca Rossi,G. Iapichino,G. Romagnoli,L. Uziel,Angelo Agostoni +9 more
TL;DR: Extracorporeal carbon dioxide removal with low-frequency ventilation proved a safe technique, and it is suggested as a valuable tool and an alternative to treating severe acute respiratory failure by conventional means.
Journal ArticleDOI
Role of Tidal Volume, FRC, and End-inspiratory Volume in the Development of Pulmonary Edema following Mechanical Ventilation
Didier Dreyfuss,Georges Saumon +1 more
TL;DR: Hemodynamic status plays an important role in modulating the amount of edema during lung overinflation but does not fundamentally modify the characteristics of this edema which is consistently associated with major permeability alterations.