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Laser speckle imaging with an active noise reduction scheme

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TLDR
It is shown experimentally that for this scheme spatial and temporal averaging provide the same statistical weight to reduce the noise in LSI: the standard deviation of the speckle contrast value scales with the effective number N of independent speckles as 1/ radicalN.
Abstract
We present an optical scheme to actively suppress statistical noise in Laser Speckle Imaging (LSI). This is achieved by illuminating the object surface through a diffuser. Slow rotation of the diffuser leads to statistically independent surface speckles on time scales that can be selected by the rotation speed. Active suppression of statistical noise is achieved by accumulating data over time. We present experimental data on speckle contrast and noise for a dynamically homogenous and a heterogeneous object made from Teflon. We show experimentally that for our scheme spatial and temporal averaging provide the same statistical weight to reduce the noise in LSI: The standard deviation of the speckle contrast value scales with the effective number N of independent speckle as 1/ radicalN.

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Journal ArticleDOI

Review of laser speckle contrast techniques for visualizing tissue perfusion.

TL;DR: The contribution of laser speckle contrast techniques to the field of perfusion visualization is presented and the development of the techniques are discussed.
Journal ArticleDOI

Can laser speckle flowmetry be made a quantitative tool

TL;DR: The underlying theory is reviewed, the impact of various analytic models for relating measured intensity fluctuations to scatterer motion is explored, and some of the practical issues associated with the measurement and subsequent data processing are addressed.
Journal Article

Laser speckle contrast imaging for measuring blood flow

J. David Briers
- 01 Jan 2007 - 
TL;DR: In this article, the authors reviewed the development of laser speckle imaging, starting with the connection established between speckles fluctuations and movement in the nineteen-seventies, and ten years later a digital version was used to monitor retinal blood flow.
Journal ArticleDOI

Laser Speckle Contrast Imaging: Theory, Instrumentation and Applications

TL;DR: The theory and practice of LSCI is discussed and its merit is critically analyzed in major areas of application such as retinal imaging, imaging of skin perfusion as well as imaging of neurophysiology.
References
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Journal ArticleDOI

Diffusing wave spectroscopy

TL;DR: A phenomenological model, which exploits the diffusive nature of the transport of light, is shown to be in excellent agreement with experimental data for several different scattering geometries, and the dependence on geometry provides an important experimental control over the time scale probed.
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Dynamic Imaging of Cerebral Blood Flow Using Laser Speckle

TL;DR: Using this method, dynamic images of the relative CBF changes during focal cerebral ischemia and cortical spreading depression were obtained along with electrophysiologic recordings and validated through direct comparison with conventional laser-Doppler measurements.
Journal ArticleDOI

Laser Doppler, speckle and related techniques for blood perfusion mapping and imaging

TL;DR: This review article presents the theory and practice of these techniques using a tutorial approach and compares the relative merits of the scanning and full-field approaches to velocity map imaging and concludes with a review of reported applications ofThese techniques to blood perfusion mapping and imaging.
Journal ArticleDOI

Laser speckle contrast analysis (LASCA): a nonscanning, full-field technique for monitoring capillary blood flow

TL;DR: A new noninvasive technique for monitoring capillary blood flow based on the phenomenon of time-varying laser speckle, which provides a velocity map of the area of interest in real time without the need for scanning.
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