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Left ventricular radius to wall thickness ratio.

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TLDR
Measurement of left ventricular relative wall thickness appears to provide diagnostic and prognostic data in patients with a broad variety of cardiac disorders.
Abstract
Left ventricular relative wall thickness, expressed as the ratio of end-diastolic radius to wall thickness (R/Th ratio), has a constant relation with left ventricular systolic pressure in children and adults with a normal heart, subjects with physiologic forms of cardiac hypertrophy (athletes) and patients with compensated chronic left ventricular volume overload (chronic aortic regurgitation). Greatly increased values for the radius/thickness ratio, suggesting inadequate hypertrophy, indicate a poor prognosis in patients with chronic aortic regurgitation and in those with congestive cardiomyopathy; decreased values for this ratio are found in patients with hypertrophic cardiomyopathy (inappropriate hypertrophy) and in patients with compensated aortic stenosis (appropriate hypertrophy). In patients with compensated aortic stenosis, echocardiographic measurement of the left ventricular end-diastolic radius/wall thickness ratio has been used to estimate left ventricular systolic pressure. Measurement of left ventricular relative wall thickness appears to provide diagnostic and prognostic data in patients with a broad variety of cardiac disorders.

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ACC/AHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease

TL;DR: It is important that the medical profession play a significant role in critically evaluating the use of diagnostic procedures and therapies as they are introduced in the detection, management, and management of diseases.
Journal ArticleDOI

Patterns of left ventricular hypertrophy and geometric remodeling in essential hypertension

TL;DR: Correspondence of left ventricular mass in concentric remodeling appeared to reflect offsetting by volume "underload" of the effects of pressure overload, whereas eccentric hypertrophy was associated with concomitant pressure and volume overload.
References
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Journal ArticleDOI

Recommendations regarding quantitation in M-mode echocardiography: results of a survey of echocardiographic measurements.

TL;DR: The survey shows significant interobserver and interlaboratory variation in measurement when examining the same echoes and indicates a need for ongoing education, quality control and standardization of measurement criteria.
Journal ArticleDOI

Wall stress and patterns of hypertrophy in the human left ventricle.

TL;DR: The hypothesis that hypertrophy develops to normalize systolic but not diastolic wall stress is suggested, and it is proposed that increased syStolic tension development by myocardial fibers results in fiber thickening just sufficient to return the systolics stress (force per unit cross-sectional area) to normal.
Journal ArticleDOI

Left ventricular compliance: mechanisms and clinical implications.

TL;DR: The pathophysiology of pulmonary congestion is best understood by considering the factors responsible for producing changes in chamber stiffness of the ventricle, whereas an examination of muscle stiffness is likely to provide more insight into the extent of irreversible functional and structural defects of the myocardium.
Journal ArticleDOI

Effects of a natural volume overload state (pregnancy) on left ventricular performance in normal human subjects.

R Katz, +2 more
- 01 Sep 1978 - 
TL;DR: It is concluded that a temporary volume overload state in normal humans results in hemodynamic adjustments often observed in cardiac decompensation (increased heart rate and size), however, left ventricular function, although not augmented, is well preserved, thereby leading to an increase in minute output.
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