Journal ArticleDOI
Levothyroxine Therapy in Patients with Thyroid Disease
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TLDR
For some patients with nodular thyroid disease, conflicting or insufficient data may not allow an unequivocal consensus recommendation, and in such circumstances, the existing evidence is reviewed and a rational strategy for treatment is provided.Abstract:
Purpose: To review the indications for and the proper monitoring of levothyroxine therapy in patients with thyroid disease. Data Sources: Relevant English language articles published from 1966 to 1...read more
Citations
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Journal ArticleDOI
Management of Thyroid Dysfunction during Pregnancy and Postpartum: An Endocrine Society Clinical Practice Guideline
Leslie J. De Groot,Marcos Abalovich,Erik K. Alexander,Nobuyuki Amino,Linda A. Barbour,Rhoda H. Cobin,Creswell J Eastman,John H. Lazarus,Dominique Luton,Susan J. Mandel,Jorge H. Mestman,Joanne Rovet,Scott Sullivan +12 more
TL;DR: Practice guidelines are presented for diagnosis and treatment of patients with thyroid-related medical issues just before and during pregnancy and in the postpartum interval, including evidence-based approaches to assessing the cause of the condition, treating it, and managing hypothyroidism.
Journal ArticleDOI
Clinical Practice Guidelines for Hypothyroidism in Adults: Cosponsored by the American Association of Clinical Endocrinologists and the American Thyroid Association
Jeffrey R. Garber,Jeffrey R. Garber,Rhoda H. Cobin,Hossein Gharib,James V. Hennessey,Irwin Klein,Jeffrey I. Mechanick,Rachel Pessah-Pollack,Peter Singer,Kenneth A. Woeber +9 more
TL;DR: Fifty-two evidence-based recommendations and subrecommendations were developed to aid in the care of patients with hypothyroidism and to share what the authors believe is current, rational, and optimal medical practice for the diagnosis and care of hyp Timothyroidism.
Journal ArticleDOI
Guidelines for the Treatment of Hypothyroidism: Prepared by the American Thyroid Association Task Force on Thyroid Hormone Replacement
Jacqueline Jonklaas,Antonio C. Bianco,Andrew J. Bauer,Kenneth D. Burman,Anne R. Cappola,Francesco S. Celi,David S. Cooper,Brian W. Kim,Robin P. Peeters,M. Sara Rosenthal,Anna M. Sawka +10 more
TL;DR: It is concluded that levothyroxine should remain the standard of care for treating hypothyroidism and no consistently strong evidence for the superiority of alternative preparations is found.
Journal ArticleDOI
Chronic Autoimmune Thyroiditis
TL;DR: In 1912, Hashimoto described four women in whom the thyroid gland was enlarged and appeared to have been transformed into lymphoid tissue (“struma lymphomatosa”), which is now recognized as a form of chronic autoimmune thyroiditis.
Journal ArticleDOI
Clinical practice guidelines for hypothyroidism in adults: cosponsored by the American Association of Clinical Endocrinologists and the American Thyroid Association.
Garber,Rhoda H. Cobin,Hossein Gharib,James V. Hennessey,Irwin Klein,Jeffrey I. Mechanick,Rachel Pessah-Pollack,Peter Singer,Kenneth A. Woeber +8 more
TL;DR: Fifty-two evidence-based recommendations and subrecommendations were developed to aid in the care of patients with hypothyroidism and to share what the authors believe is current, rational, and optimal medical practice for the diagnosis and care of hyp Timothyroidism.
References
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Journal ArticleDOI
The spectrum of thyroid disease in a community: the whickham survey
W.M.G. Tunbridge,D. C. Evered,Reginald Hall,D. Appleton,M Brewis,F. Clark,J G Evans,E. T. Young,T. Bird,P. A. Smith +9 more
TL;DR: TSH levels above 6 mu/1 were shown to reflect a significant lowering of circulating thyroxine levels and showed a strong association with thyroid antibodies in both sexes, independent of age.
Journal ArticleDOI
Natural history, treatment, and course of papillary thyroid carcinoma.
TL;DR: The data strongly support the use of more extensive initial surgery in class I and II patients with tumors more than 1 cm in size as well as postoperative radioactive 131I ablation of thyroid remnant tissue.
Journal Article
An expanded view of risk-group definition in differentiated thyroid carcinoma.
Blake Cady,Ricardo L. Rossi +1 more
TL;DR: This work offers here another multifactorial system for the identification of low-risk patients who made up 89.4% of all patient seen between 1961 and 1980 and who have a death rate of only 1.8%.
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Type I iodothyronine deiodinase is a selenocysteine-containing enzyme
TL;DR: It is found that the mRNA for this enzyme contains a UGA codon for selenocysteine which is necessary for maximal enzyme activity and explains why conversion of T4 to T3 is impaired in experimental selenium deficiency2–6 and identifies an essential role for this trace element in thyroid hormone action.
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Follicular Thyroid Cancer Treated at the Mayo Clinic, 1946 Through 1970: Initial Manifestations, Pathologic Findings, Therapy, and Outcome
TL;DR: The overall mortality observed at 30 years was only 3% above that expected, and death from thyroid cancer was highly associated with the following factors: age more than 50 years, male sex, tumor size, tumor grade, initial extent of disease, and absence of Hashimoto's disease.