Journal ArticleDOI
Light and electron microscope study of chlorobiphenyl poisoning. In mouse and monkey liver.
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Looking at the effects on mouse and monkey liver of long-term oral administration of chlorobiphenyls (CBP), characteristic lesions of liver cells were produced by administration of CBP.Abstract:
The effects on mouse and monkey liver of long-term oral administration of chlorobiphenyls (CBP), 1.5 mg/day or more, have been investigated at selected intervals by light and electron microscopy. H...read more
Citations
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Journal ArticleDOI
The toxicity of polychlorinated polycyclic compounds and related chemicals.
TL;DR: The Toxicity of Polychlorinated Polycyclic Compounds and Related Chemicals: Critical Reviews in Toxicology: Vol.
Journal ArticleDOI
Current status of PCB toxicity to mink, and effect on their reproduction.
TL;DR: PCB toxicity experiments revealed that mink are very sensitive to these compounds and that the lethal dose varied inversely with the chlorine content of the PCB's although only Aroclor 1254 exerted a detrimental effect on reproduction when fed at a low level (2 ppm) for 8 months.
Journal ArticleDOI
World PCBs map: storage and effects in man and his biologic environment in the 1970s.
TL;DR: There is need for an integrated approach, consisting of epidemiologic studies on high risk groups in the general population and in persons occupationally exposed, as well as periodic assessment of PCB residues in man, his food, and feed supplies.
Journal ArticleDOI
Morphological changes in livers of rats fed polychlorinated biphenyls: light microscopy and ultrastructure.
TL;DR: The effect of Aroclor 1254 on the liver was more pronounced than that of A RoClor 1260, and the epithelial component of adenofibrosis consisted of goblet cells and cells that resembled the epithelium which lines the bile ducts.
Journal ArticleDOI
Hepatotoxicity induced by the anti-oxidant food additive, butylated hydroxytoluene (BHT), in rats: an electron microscopical study.
A. M. Safer,A. J. Al-Nughamish +1 more
TL;DR: Whether or not BHT acts as a carcinogen in long-term administration may depend not only upon the organ system examined, but also on the strain of the animal used.
References
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Journal ArticleDOI
Elektronen- und lichtmikroskopische Untersuchungen am Cytoplasma der Leberzellen nach akuter und chronischer Thioacetamid-Vergiftung
W. Thoenes,P. Bannasch +1 more
TL;DR: After acute and chronic poisoning with thioacetamide (TAA) the following morphologic changes appear in the cytoplasm of hepatic cells: Theergastoplasm becomes disorganized, in the sense of chromatolysis, and quantitatively diminished, or even completely dissolved, especially after short-termed high doses of TAA.
Journal ArticleDOI
An acneform dermatergosis
Jack W. Jones,Herbert S. Alden +1 more
TL;DR: More and more dermatologists are becoming industrially minded, and it is dawning on them that the solution of some of their industrial difficulties may aid them in a clearer conception of the dermatoses that are encountered in their every-day work.
Journal ArticleDOI
Chloracne from an unusual exposure to arochlor.
TL;DR: During World War II, various reports of acne-like lesions in workers exposed to certain chlorinated naphthalenes and diphenyls followed, which concerned the involvement of electricians, who installed and stripped wires in ships during the war.
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