Journal ArticleDOI
Light and electron microscope study of chlorobiphenyl poisoning. In mouse and monkey liver.
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TLDR
Looking at the effects on mouse and monkey liver of long-term oral administration of chlorobiphenyls (CBP), characteristic lesions of liver cells were produced by administration of CBP.Abstract:
The effects on mouse and monkey liver of long-term oral administration of chlorobiphenyls (CBP), 1.5 mg/day or more, have been investigated at selected intervals by light and electron microscopy. H...read more
Citations
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Cómo se altera el metabolismo y transporte de glucosa en porfiria experimental crónica y aguda. Una aproximación mecanística
TL;DR: Wistar et al. as mentioned in this paper used ratas Wistar como animales de experimentacion and drogas tales such as el hexaclorobenceno for inducir porfiria cronica, and the 2-alil-2-isopropilacetamida junto with 3´,5´-dietoxicarbonil-1,4- dihidrocolidina, to modelar una porfirus aguda.
Ultrastructural alterations in the liver of rats fed photomirex
TL;DR: It is concluded that photomirex causes more severe ultrastructural changes in the livers of rats than mirex.
Journal ArticleDOI
Studies on Experimental PCB poisoning
TL;DR: Analysis of rats of the Wistar strain revealed that the weight of the liver was increased, the liver and serum cholesterol content was increased), the liver aniline hydroxylase activity was increased and the liver Na-K-Mg-dependent ATPase was decreased in the PCB fed group.
Journal ArticleDOI
The effects of 1,1-di(p-chlorophenyl)-2-chloroethylene (DDMU) on hepatic morphology of Japanese quail.
TL;DR: The effects of dietary administration of 1,1-di(p-chlorophenyl)-2-chloroethylene to Japanese quail at a concentration of 100 ppm were investigated for periods of up to 32 days and histologic changes observed included cytoplasmic and nuclear degeneration in the hepatocytes followed by severe lipid accumulation and hepatocellular hypertrophy.
References
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Journal ArticleDOI
Improvements in epoxy resin embedding methods.
TL;DR: Epoxy embedding methods of Glauert and Kushida have been modified so as to yield rapid, reproducible, and convenientembedding methods for electron microscopy.
Journal ArticleDOI
Staining of Tissue Sections for Electron Microscopy with Heavy Metals
TL;DR: Certain hitherto unobserved details are revealed and some sort of specificity exists, although the factors involved are not yet understood.
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A modified procedure for lead staining of thin sections.
TL;DR: Among several heavy metal salts tested, the above-ment ioned " lead hydroxide" of Watson seemed to be the most effective in "s ta in ing ." Exper iments with the commercial ly available product showed that this salt would give no impregna t ion when dissolved in water, or in Institute.
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A method for staining epoxy sections for light microscopy.
TL;DR: A technique for staining sections of osmium-fixed, epoxy-embedded tissues for light microscopy using aqueous toluidine blue at pH 11.1 and does not require prior removal of embedding medium, which permits better utilization of the full resolving power of the light microscope.
Journal ArticleDOI
s-Collidine as a Basis for Buffering Fixatives
H. Stanley Bennett,John H. Luft +1 more
TL;DR: The search for a medium which might offer improvements from the point of view of stability and buffering capacity for Palade's buffered osmic fixative was focused on s-collidine, which has a pK of about 7.4.
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