Patent
Lipid-polymer conjugates and liposomes
TLDR
In this paper, a lipid-polymer conjugate for long-circulating liposomes is presented. But the conjugates do not include a vesicle-forming lipid having convalently attached to its polar head group, such as polyvinylpyrrolidone or polyaspartamide.Abstract:
A lipid-polymer conjugate for use in forming long-circulating liposomes is disclosed. The conjugate includes a vesicle-forming lipid having convalently attached to its polar head group, one of the polymers: polyvinylpyrrolidone, polyvinylmethylether, polyhydroxypropyl methacrylate, polyhydroxypropylmethacrylamide, polyhydroxyethyl acrylate, polymethacrylamide, polydimethylacrylamide, polymethyloxazoline, polyethyloxazoline, polyhydroxyethyloxazoline, polyhydroxypropyloxazoline, or polyaspartamide. A method for preparing liposomes containing the lipid-polymer conjugate is also disclosed.read more
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References
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Journal ArticleDOI
Comparative Properties and Methods of Preparation of Lipid Vesicles (Liposomes)
TL;DR: This research attacked the mode of action of phosphatidylcholine-like deposits in response to the presence of ribonucleic acid by exploiting its role as a “spatially aggregating substance” in the response to EMT.
Book
Poly(ethylene glycol) chemistry : biotechnical and biomedical applications
TL;DR: PEG Derivatized Ligands with Hydrophobic and Immunological Specificity and Preparation and Properties of Monomethoxypoly(Ethylene Glycol)Modified Enzymes for Therapeutic Applications.
Patent
Liposomes with enhanced circulation time
TL;DR: A liposome composition which contains between 1-20 mole percent of an amphipathic lipid derivatized with a polyalkylether, as exemplified by phosphatidylethanolamine derivatised with polyethyleneglycol, is described in this article.
Journal Article
Biological approaches to the controlled delivery of drugs: a critical review.
M J Poznansky,R L Juliano +1 more
Book
Water-Soluble Synthetic Polymers: Volume I: Properties and Behavior
TL;DR: In this article, the physical chemistry of water-soluble synthetic polymers as a group is surveyed and compared, and their properties and behaviour is correlated with their molecular structures for predictive purposes, and sufficient key recent references are also included so that the existing state of the art is delineated.