P
P. Mickey Williams
Researcher at Genentech
Publications - 103
Citations - 5404
P. Mickey Williams is an academic researcher from Genentech. The author has contributed to research in topics: Nucleic acid & Peptide sequence. The author has an hindex of 21, co-authored 103 publications receiving 5104 citations. Previous affiliations of P. Mickey Williams include Philips.
Papers
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Journal ArticleDOI
Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis
Heidi S. Phillips,Samir Kharbanda,Ruihuan Chen,William F. Forrest,Robert Soriano,Thomas D. Wu,Anjan Misra,Janice Nigro,Howard Colman,Liliana Soroceanu,P. Mickey Williams,Zora Modrusan,Burt G. Feuerstein,Kenneth Aldape +13 more
TL;DR: Previously undescribed prognostic subclasses of high-grade astrocytoma are identified and discovered to resemble stages in neurogenesis, suggesting functional relevance of tumor subtype molecular signatures is suggested by the ability of cell line signatures to predict neurosphere growth.
Journal ArticleDOI
Fibroblast growth factor 19 increases metabolic rate and reverses dietary and leptin-deficient diabetes.
Ling Fu,Linu M. John,Sean H. Adams,Xing Xian Yu,Elizabeth Tomlinson,Mark Renz,P. Mickey Williams,Robert Soriano,Racquel Corpuz,Barbara Moffat,Richard Vandlen,Laura C. Simmons,Jessica Foster,Jean Philippe Stephan,Siao Ping Tsai,Timothy A. Stewart +15 more
TL;DR: Treatment with FGF19 prevented or reversed the diabetes that develops in mice made obese by genetic ablation of brown adipose tissue or genetic absence of leptin, and profiled the F GF19-induced gene expression changes in the liver and brown fat.
Patent
Compositions and methods for the diagnosis and treatment of tumor
Belinda Cairns,Ruihuan Chen,Gretchen Frantz,Kenneth J. Hillan,Hartmut Koeppen,Heidi S. Phillips,Paul Polakis,Susan D. Spencer,Victoria Smith,P. Mickey Williams,Thomas D. Wu,Zemin Zhang +11 more
TL;DR: In this article, an antibody drug conjugate composition of matter useful for the diagnosis and treatment of tumors in mammals and methods of using those compositions of matter for the same were described.
Patent
Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis
Kevin P. Baker,Napoleone Ferrara,Hans-Peter Gerber,Mary E. Gerritsen,Audrey Goddard,Paul J. Godowski,Austin L. Gurney,Kenneth J. Hillan,Scot A. Marsters,James Pan,Nicholas F. Paoni,Jean-Philippe Stephan,Colin K. Watanabe,P. Mickey Williams,William I. Wood,Weilan Ye +15 more
TL;DR: In this article, the authors present compositions and methods for stimulating or inhibiting angiogeniesis and/or cardiovascularization in mammals, including humans, using polypeptides or antagonists that have been identified for one or more of these uses.