Journal ArticleDOI
Localized detection and classification of abnormalities on FFDM and tomosynthesis examinations rated under an FROC paradigm.
David Gur,Andriy I. Bandos,Howard E. Rockette,Margarita L. Zuley,Jules H. Sumkin,Denise M. Chough,Christiane M. Hakim +6 more
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TLDR
It is shown that DBT-based breast imaging in combination with FFDM could result in better performance under the free-response receiver operating characteristic (FROC) paradigm, and each of the radiologists performed better under the combined mode compared with FF DM alone.Abstract:
OBJECTIVE. The purpose of our study was to assess diagnostic performance when retrospectively interpreting full-field digital mammography (FFDM) and breast tomosynthesis examinations under a free-response receiver operating characteristic (FROC) paradigm.MATERIALS AND METHODS. We performed FROC analysis of a previously reported study in which eight experienced radiologists interpreted 125 examinations, including 35 with verified cancers. The FROC paradigm involves detecting, locating, and rating each suspected abnormality. Radiologists reviewed and rated both FFDM alone and a combined display mode of FFDM and digital breast tomosynthesis (DBT) (combined). Observer performance levels were assessed and compared with respect to the fraction of correctly identified abnormalities, the number of reported location-specific findings (both true and false), and their associated ratings. The analysis accounts for the number and locations of findings and the location-based ratings using a summary performance index (Λ...read more
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Prospective trial comparing full-field digital mammography (FFDM) versus combined FFDM and tomosynthesis in a population-based screening programme using independent double reading with arbitration
Per Skaane,Andriy I. Bandos,Randi Gullien,Ellen B. Eben,Ulrika Ekseth,Unni Haakenaasen,Mina Izadi,Ingvild N. Jebsen,Gunnar Jahr,Mona Krager,Solveig Hofvind +10 more
TL;DR: Double reading of 2D + 3D significantly improves the cancer detection rate in mammography screening and significantly reduced false-positive interpretations in tomosynthesis-based examinations.
Journal ArticleDOI
Digital Breast Tomosynthesis: State of the Art.
TL;DR: The observations of increase in cancer detection rates, particularly for invasive cancers, and the reduction in false-positive rates with DBT in prospective trials indicate its benefit for breast cancer screening.
Journal ArticleDOI
Comparison of Two-dimensional Synthesized Mammograms versus Original Digital Mammograms Alone and in Combination with Tomosynthesis Images
Margarita L. Zuley,Ben Guo,Victor J. Catullo,Denise M. Chough,Amy E. Kelly,Amy Lu,Grace Y. Rathfon,Marion Lee Spangler,Jules H. Sumkin,Luisa P. Wallace,Andriy I. Bandos +10 more
TL;DR: SM alone or in combination with tomosynthesis is comparable in performance to FFDM alone orIn combination withTomosynthesis and may eliminate the need for FFDM as part of a routine clinical study.
Journal ArticleDOI
Overview of the evidence on digital breast tomosynthesis in breast cancer detection.
Nehmat Houssami,Per Skaane +1 more
TL;DR: Preliminary data from population screening trials suggest that the integration of DBT with conventional DM may substantially improve breast cancer detection, although final results are not yet available, and many logistical issues need further evaluation to determine the potential implications and cost of combined 2D + 3D mammographic screening.
Journal ArticleDOI
Digital Breast Tomosynthesis versus Supplemental Diagnostic Mammographic Views for Evaluation of Noncalcified Breast Lesions
Margarita L. Zuley,Andriy I. Bandos,Marie A. Ganott,Jules H. Sumkin,Amy E. Kelly,Victor J. Catullo,Grace Y. Rathfon,Amy Lu,David Gur +8 more
TL;DR: Tomosynthesis significantly improved diagnostic accuracy for noncalcified lesions compared with supplemental mammographic views compared with BI-RADS category 4 or 5, without a meaningful change in sensitivity.
References
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Journal ArticleDOI
Digital tomosynthesis in breast imaging.
Loren T. Niklason,B T Christian,L E Niklason,Daniel B. Kopans,D E Castleberry,Beale Opsahl-Ong,C E Landberg,Priscilla J. Slanetz,Angela A. Giardino,Richard D. Moore,D Albagli,M C DeJule,Paul Fitzgerald,D F Fobare,B W Giambattista,R F Kwasnick,J Liu,S J Lubowski,G E Possin,J F Richotte,C Y Wei,R F Wirth +21 more
TL;DR: Tomosynthesis may improve the specificity of mammography with improved lesion margin visibility and may improve early breast cancer detection, especially in women with radiographically dense breasts.
Journal ArticleDOI
Digital breast tomosynthesis: initial experience in 98 women with abnormal digital screening mammography.
TL;DR: In this article, the authors compared the image quality of tomosynthesis with that of conventional mammography and estimated the recall rate of screening when Tomosynthesis is used in addition to mammography.
Journal ArticleDOI
Digital breast tomosynthesis: observer performance study.
David Gur,Gordon S. Abrams,Denise M. Chough,Marie A. Ganott,Christiane M. Hakim,Ronald L. Perrin,Grace Y. Rathfon,Jules H. Sumkin,Margarita L. Zuley,Andriy I. Bandos +9 more
TL;DR: Use of digital breast tomosynthesis for breast imaging may result in a substantial decrease in recall rate, and there was no convincing evidence that use of digital Breast Tomosynthesis alone or in combination with FFDM results in a significant improvement in sensitivity.
Journal ArticleDOI
Observer studies involving detection and localization: modeling, analysis, and validation.
TL;DR: A new jackknife FROC analysis method (JAFROC) that does not make the independence assumption is proposed, which suggests that future studies of diagnostic performance may enjoy improved statistical power or reduced sample size requirements through the use of this method.
Journal ArticleDOI
A comparison of reconstruction algorithms for breast tomosynthesis.
TL;DR: It was shown in both phantom imaging and patient imaging that the BP algorithm provided the best SDNR for low-contrast masses but the conspicuity of the feature details was limited by interplane artifacts; the FBP algorithms provided the highest edge sharpness for microcalcifications but the quality of masses was poor.