Journal ArticleDOI
Malarial antibodies and autoantibodies to heart and other tissues in the immigrant and indigenous peoples of uganda
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TLDR
An immunological syndrome consisting of high titres of malarial antibody and the presence of high levels of IgM and circulating autoantibodies to heart, thyroid, and gastric parietal cells has been delineated in immigrant and indigenous peoples of Uganda.About:
This article is published in The Lancet.The article was published on 1968-06-22. It has received 93 citations till now. The article focuses on the topics: Endomyocardial fibrosis.read more
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Cooperating and controlling functions of thymus-derived lymphocytes in relation to autoimmunity.
TL;DR: Evidence is presented that T cells can exert specific feedback control of autoantibody formation and relaxation of T-cell control in ageing humans and experimental animals may be an important contributory factor in the development of autoimmunity.
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Autoimmune disease and parasitic infections in Nigerians.
TL;DR: Analysis of the pattern of admissions to University College Hospital, Ibadan, Nigeria, shows that diseases in which autoimmune processes are thought to be involved are uncommon in Western Nigeria, and the results of a population survey into the prevalence of rheumatoid arthritis support this view.
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Löffler's endocarditis and Davies' endomyocardial fibrosis
TL;DR: A review of the literature on 90 cases of endomyocardial lesions associated with eosinophilia and a personal study of the histology of 30 cases showed that Loffler's endocarditis (in the fibrotic stage) could not be distinguished histology from Davies' E.M.F.
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Possible role of a B-cell mitogen in hypergammaglobulinaemia in malaria and trypanosomiasis.
TL;DR: Serum-immunoglobulins, especially IgM, increase considerably in patients with malaria and trypanosomiasis, and this immunoglobulin contains not only specific anti-parasite antibodies but also antibodies reacting with other non-Parasite antigenic determinants, including those of host tissue.
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Malaria and human polymorphisms.
TL;DR: The characteristic symptoms of malaria, tertian or quartan fever and an enlarged spleen, were specifically recorded in Greece by Hippocrates in the 4th century B .
References
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Journal ArticleDOI
Localization of antigen in tissue cells ii. improvements in a method for the detection of antigen by means of fluorescent antibody
Albert H. Coons,Melvin H. Kaplan +1 more
TL;DR: Improvements in a method for the specific microscopic localization of antigen in tissue cells are described and two isomeric series derived from nitrofluorescein are described.
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An epidemiologic approach to the lymphomas of african children and burkitt's sacroma of the jaws.
TL;DR: This discussion critically examines the known circumstances and proposes an alternative evaluation of the disease, based on information from the Kenya Cancer Registry and on field and laboratory investigations.
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Geographical and Tribal Distribution of the African Lymphoma in Uganda
Denis Burkitt,Dennis H. Wright +1 more
TL;DR: Andrews, G. W, and Sellors, T. H. (1962).
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Immunologic studies of heart tissue. IV. Serologic reactions with human heart tissue as revealed by immunofluorescent methods: isoimmune, Wassermann, and autoimmune reactions.
TL;DR: Serologic reactions with homologous or autologous heart were observed particularly frequently with sera from rheumatic patients approximately 2 weeks following cardiac surgery, as well as in some non-rheumatic Patients following cardiac or thoracic surgery or acute myocardial infarction.