Open AccessJournal Article
Management of refractory idiopathic overactive bladder: intradetrusor injection of botulinum toxin type A versus posterior tibial nerve stimulation.
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TLDR
Intradetrusor injection of BTX-A and PTNS are both effective to manage refractory idiopathic OAB, and BTx-A is more effective than PTNS and is also durable, minimally invasive, reversible, and safe, but it also has more side effects.Abstract:
Introduction To compare the safety and efficacy of posterior tibial nerve stimulation (PTNS) versus an intradetrusor injection of botulinum toxin type-A (BTX-A) 100 U in the management of refractory idiopathic overactive bladder (OAB). Materials and methods We randomized 60 patients with refractory idiopathic OAB to receive an intradetrusor injection of BTX-A 100 U or PTNS. We assessed the patients at baseline, 6 weeks, 3 months, 6 months, and 9 months, and determined their clinical symptoms, overall OAB symptom score, urgency score, quality-of-life score, and urodynamic study parameters. Results The two patient groups had similar baseline characteristics. After treatment, the patients in the BTX-A group had significant improvements in all parameters compared to their baseline values. Patients in the PTNS group initially had significant improvements in all parameters, but by 9 months, this was no longer true for most parameters. In general, the improvements were more significant in the BTX group, especially at 9 months. In the BTX-A group, two patients (6.6%) needed clean intermittent catheterization; 3 patients (2 women and 1 man; 10% of patients) had mild hematuria, and 2 patients (6.6%) had urinary tract infections (UTIs). In the PTNS group, local adverse effects included minor bleeding spots and temporary pain. Conclusions Intradetrusor injection of BTX-A and PTNS are both effective to manage refractory idiopathic OAB. BTX-A is more effective than PTNS and is also durable, minimally invasive, reversible, and safe, but it also has more side effects.read more
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Journal ArticleDOI
Long-term durability of percutaneous tibial nerve stimulation for the treatment of overactive bladder
TL;DR: The authors provide an excellent technical analysis and state that when using this technique they are able to salvage approximately three out of four patients, which has a potential to achieve a great deal of popularity in this very difficult to treat population.
Journal ArticleDOI
Management of Idiopathic Overactive Bladder Syndrome: What Is the Optimal Strategy After Failure of Conservative Treatment?
Tom Marcelissen,Tom Marcelissen,Jean-Nicolas Cornu,Tiago Antunes-Lopes,Tiago Antunes-Lopes,Bogdan Geavlete,Nicolas Barry Delongchamps,Nicolas Barry Delongchamps,Tina Rashid,Tina Rashid,Malte Rieken,Malte Rieken,Mohammad S. Rahnama'i,Mohammad S. Rahnama'i,Mohammad S. Rahnama'i +14 more
TL;DR: The available literature assessing therapeutic effect of the available third-line treatment modalities for OAB shows none of the mentioned therapeutic modalities shows strong superiority over another.
Journal ArticleDOI
Comparing the efficacy of onabotulinumtoxinA, sacral neuromodulation, and peripheral tibial nerve stimulation as third line treatment for the management of overactive bladder symptoms in adults: Systematic review and network meta-analysis
TL;DR: SNM resulted in the greatest reduction in urinary incontinence episodes and voiding frequency, however, comparison of their long-term efficacy was lacking, and further studies on the long- term effectiveness of the three treatment options, with standardized questionnaires and parameters are warranted.
Journal ArticleDOI
Percutaneous tibial nerve stimulation for idiopathic and neurogenic overactive bladder dysfunction: a four-year follow-up single-centre experience.
TL;DR: Percutaneous tibial nerve stimulation (PTNS) is endorsed in the literature as mentioned in this paper for overactive bladder (OAB) affects hundreds of millions of people worldwide and has significant detrimental effects on quality-of-life.
Journal ArticleDOI
Comparison of transcutaneous tibial nerve stimulation (TTNS) protocols for women with refractory overactive bladder (OAB): A prospective randomised trial.
TL;DR: In this paper, the effectiveness of the TTNS procedure applied once a week and three times a week in women diagnosed with wet type refractory OAB was compared between groups, and no significant difference was observed between the groups in terms of treatment response.
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Updated Systematic Review and Meta-analysis of the Comparative Data on Colposuspensions, Pubovaginal Slings, and Midurethral Tapes in the Surgical Treatment of Female Stress Urinary Incontinence
Giacomo Novara,Walter Artibani,Matthew D. Barber,Christopher R. Chapple,Elisabetta Costantini,Vincenzo Ficarra,Paul Hilton,Carl Gustaf Nilsson,David Waltregny +8 more
TL;DR: In this paper, the authors evaluated the efficacy, complication, and reoperation rates of midurethral tapes compared with other surgical treatments for female SUI, and found that patients treated with RT experienced slightly higher continence rates than those treated with Burch colposuspension, but they faced a much higher risk of intraoperative complications.
Journal ArticleDOI
Treatment of Motor and Sensory Detrusor Instability by Electrical Stimulation
TL;DR: In patients treated successfully for detrusor instability an absence of urgency occurred as a by-product of electrical stimulation, so stimulation was used to treat uncomfortable bladder urgency without det Rusor instability and was successful in the majority of patients.
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