Journal ArticleDOI
Mechanical behaviour of synthetic surgical meshes: Finite element simulation of the herniated abdominal wall
B. Hernández-Gascón,Estefanía Peña,H. Melero,Gemma Pascual,Manuel Doblaré,Maria-Pau Ginebra,Juan M. Bellón,Begoña Calvo +7 more
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TLDR
Finite element simulation of the healthy and partially herniated repaired rabbit abdominal wall served to reproduce wall behaviour before and after mesh implant, and the Infinit® mesh was able to best comply with the biomechanics of the abdominal wall.About:
This article is published in Acta Biomaterialia.The article was published on 2011-11-01. It has received 93 citations till now. The article focuses on the topics: Surgical Mesh Implant & Surgical mesh.read more
Citations
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Journal ArticleDOI
Mechanical properties of the abdominal wall and biomaterials utilized for hernia repair
Corey R. Deeken,Spencer P. Lake +1 more
TL;DR: The studies reviewed here reported greater compliance of the linea alba, larger strains for the intact abdominal wall, and greater stiffness for the rectus sheath and umbilical fascia when the tissues were loaded in the longitudinal direction compared to transverse.
Journal ArticleDOI
ECM hydrogel coating mitigates the chronic inflammatory response to polypropylene mesh.
Denver M. Faulk,Ricardo Londono,Matthew T. Wolf,Christian A. Ranallo,Christopher A. Carruthers,Justin D. Wildemann,Christopher L. Dearth,Stephen F. Badylak +7 more
TL;DR: This study confirms and extends previous findings that an ECM coating mitigates the chronic inflammatory response and associated scar tissue deposition characteristic of polypropylene.
Journal ArticleDOI
Polypropylene Surgical Mesh Coated with Extracellular Matrix Mitigates the Host Foreign Body Response
Matthew T. Wolf,Christopher A. Carruthers,Christopher L. Dearth,Peter M. Crapo,Peter M. Crapo,Alexander Huber,Olivia A. Burnsed,Ricardo Londono,Scott A. Johnson,Kerry A. Daly,Elizabeth C. Stahl,John M. Freund,Christopher J. Medberry,Lisa E. Carey,Alejandro Nieponice,Nicholas J. Amoroso,Stephen F. Badylak +16 more
TL;DR: This study shows that an ECM coating alters the default host response to a polypropylene mesh, but not the mechanical properties in an acute in vivo abdominal repair model.
Journal ArticleDOI
Mechanical biocompatibility of highly deformable biomedical materials
TL;DR: The challenges related to the analysis and attainment of mechanical biocompatibility of soft implants are illustrated with two examples: prosthetic meshes for hernia and pelvic repair and electrospun scaffolds for tissue engineering.
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Retrieval study at 623 human mesh explants made of polypropylene - impact of mesh class and indication for mesh removal on tissue reaction.
B. Klosterhalfen,Uwe Klinge +1 more
TL;DR: Large pore class 1 meshes showed an improved tissue response and may be considered as favorable to prevent inflammatory side effects and the presence of lowered collagen 1/3 ratio in most of the samples with recurrences stresses the relevance of an intact healing process.
References
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Journal ArticleDOI
A new constitutive framework for arterial wall mechanics and a comparative study of material models
TL;DR: In this paper, the authors developed a constitutive law for the description of the (passive) mechanical response of arterial tissue, where the artery is modeled as a thick-walled nonlinearly elastic circular cylindrical tube consisting of two layers corresponding to the media and adventitia.
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The tension-free hernioplasty
TL;DR: With the use of modern mesh prosthetics, it is now possible to repair all hernias without distortion of the normal anatomy and with no suture line tension, allowing prompt resumption of unrestricted physical activity.