Journal ArticleDOI
Mechanism of L-ascorbic acid oxidation and dehydro-L-ascorbic acid reduction on a mercury electrode. I. Acid medium
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TLDR
A polarographic study of the oxidation mechanism of L-ascorbic acid and of the reduction mechanism of dehydro-Lascorbics was carried out in an acid medium as mentioned in this paper.Abstract:
A polarographic study of the oxidation mechanism of L-ascorbic acid and of the reduction mechanism of dehydro-L-ascorbic acid was carried out in an acid medium.For L-ascorbic acid, the oxidation pr...read more
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Journal ArticleDOI
From bench to bedside – preclinical and early clinical development of the anticancer agent indazolium trans-[tetrachlorobis(1H-indazole)ruthenate(III)] (KP1019 or FFC14A)
Christian G. Hartinger,Stefanie Zorbas-Seifried,Michael A. Jakupec,Bernd Kynast,Haralabos Zorbas,Bernhard K. Keppler +5 more
TL;DR: The preclinical and early clinical development of KP1019 - from bench to bedside - is recapitulated and promising activity against certain types of tumors is observed.
Journal ArticleDOI
KP1019, a new redox-active anticancer agent--preclinical development and results of a clinical phase I study in tumor patients.
Christian G. Hartinger,Christian G. Hartinger,Michael A. Jakupec,Stefanie Zorbas-Seifried,Michael Groessl,Alexander E. Egger,Walter Berger,Haralabos Zorbas,Paul J. Dyson,Bernhard K. Keppler +9 more
TL;DR: The experimental evidence for the proposed mode of action of this coordination compound is discussed, including transport into the cell via the transferrin cycle and activation by reduction.
Journal ArticleDOI
Simultaneous determination of dopamine, ascorbic acid and uric acid at electrochemically reduced graphene oxide modified electrode
TL;DR: In this paper, a facile electrochemical method was applied to prepare electrochemically reduced graphene oxide (ERGO), and the morphology and structure of ERGO were characterized by scanning electron microscope (SEM), X-ray photoelectron spectroscopy (XPS), Raman spectrography and Xray diffraction (XRD).
Journal ArticleDOI
Electrochemical methods for ascorbic acid determination
TL;DR: In this article, a review of electrochemical methods for ascorbic acid assessment is presented, focusing on electrochemical sensors for assessing the concentration of vitamin C in various media.
Journal ArticleDOI
Carbon Nanotube-Modified Carbon Fiber Microelectrodes for In Vivo Voltammetric Measurement of Ascorbic Acid in Rat Brain
TL;DR: Results indicate that the prepared MWNT-modified CFMEs possess a marked electrocatalytic activity toward AA oxidation and can be used for its selective measurement in the presence of other kinds of electroactive species coexisting in rat brain, such as 3,4-dihydroxyphenylacetic acid, uric acid, and 5-hydroxytryptamine.
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