Journal ArticleDOI
Mechanisms of cerebral vasodilatation in hypoxia.
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This article is published in Journal of Applied Physiology.The article was published on 1970-08-01. It has received 177 citations till now. The article focuses on the topics: Hypoxia (medical).read more
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Journal ArticleDOI
Integrative regulation of human brain blood flow
TL;DR: Mechanisms regulating cerebral blood flow (CBF), with specific focus on humans, are reviewed and the following four key theses are corroborated: that cerebral autoregulation does not maintain constant perfusion through a mean arterial pressure range of 60–150 mmHg; that there is important stimulatory synergism and regulatory interdependence of arterial blood gases and blood pressure on CBF regulation.
Journal ArticleDOI
Regulation of retinal blood flow in health and disease
Constantin J. Pournaras,E Rungger-Brändle,Charles E. Riva,Sveinn Hakon Hardarson,Einar Stefánsson +4 more
TL;DR: Correct control of the multiple pathways, such as retinal blood flow, tissue oxygenation and metabolic substrate support, aiming at restoring retinal cell metabolic interactions, may be effective in preventing damage occurring during the evolution of ischemic microangiopathies.
Journal ArticleDOI
Quantitation of cerebral blood volume in human infants by near-infrared spectroscopy
TL;DR: It is shown here that CBV can be derived from the expression CBV = (delta[HbO2] - delta [Hb])/(2.H.R.), where H is the large vessel total hemoglobin concentration and R to the cerebral-to-large vessel hematocrit ratio.
Journal ArticleDOI
Control of Cerebral Circulation in Health and Disease
TL;DR: The available, accurate, relatively simple methods of measuring CBF are discussed first and then the nature and control of CBF in health and disease are considered.
Journal ArticleDOI
The concept of coupling blood flow to brain function: Revision required?
TL;DR: Attention is directed toward the rich perivascular nerve supply to all parts of the cerebral circulation as possibly being an alternative control system allowing for rapid parallel changes in flow and neuronal activity.
Related Papers (5)
The effects of altered arterial tensions of carbon dioxide and oxygen on cerebral blood flow and cerebral oxygen consumption of normal young men
Seymour S. Kety,Carl F. Schmidt +1 more