Journal ArticleDOI
Medical use of psychostimulants: an overview.
TLDR
This overview addresses the basic chemistry, pharmacology, activity, medical uses, drug interactions and adverse side effects of the psychostimulants.Abstract:
This overview addresses the basic chemistry, pharmacology, activity, medical uses, drug interactions and adverse side effects of the psychostimulants.read more
Citations
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Journal ArticleDOI
Methylphenidate: Its Pharmacology and Uses
TL;DR: The current understanding of the mechanism of action and efficacy of methylphenidate in various clinical conditions is reviewed.
Journal ArticleDOI
A phase III, double-blind, placebo-controlled prospective randomized clinical trial of d-threo-methylphenidate HCl in brain tumor patients receiving radiation therapy.
Jerome M. Butler,L. Douglas Case,James N. Atkins,Bart Frizzell,George Sanders,Patricia C. Griffin,Glenn J. Lesser,Kevin P. McMullen,Richard P. McQuellon,Michelle J. Naughton,Stephen R. Rapp,Volker W. Stieber,Edward G. Shaw +12 more
TL;DR: Prophylactic use of d-MPH in brain tumor patients undergoing RT did not result in an improvement in QOL and there was no difference in fatigue between patient groups.
Journal ArticleDOI
The prevalence and pharmacotherapy of depression in cancer patients
TL;DR: Despite the high prevalence of depression in cancer patients, studies on effective pharmacotherapy are relatively scarce and the evidence for the efficacy of conventional medication used for the treatment of depression such as tricyclics antidepressants and selective serotonin reuptake inhibitors is very limited.
Journal ArticleDOI
Use of stimulants in the medically ill.
TL;DR: The use of psychostimulants, such as dextroamphetamine, methylphenidate, and pemoline, in a variety of illnesses, including depression in the medically ill, cancer, HIV, and AIDS are discussed.
Journal ArticleDOI
Discriminative-stimulus and participant-rated effects of methylphenidate, bupropion, and triazolam in d-amphetamine-trained humans.
TL;DR: It is demonstrated that the acute behavioral effects of d-amphetamine and methylphenidate overlap extensively in humans, which is concordant with preclinical studies and previous findings of a dissociation between the discriminative-stimulus and participant-rated effects of drugs.
References
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Journal ArticleDOI
Side Effects of Corticosteroid Therapy: Psychiatric Aspects
TL;DR: While dosage may be correlated to the risk of developing mental disturbances, neither dosage nor duration of treatment seems to affect the time of onset, duration, severity, or type of mental disturbances.
Journal ArticleDOI
A controlled study of methylphenidate in the treatment of attention deficit disorder, residual type, in adults.
TL;DR: The diagnosis of attention deficit disorder, residual type, should be considered in patients with prominent complaints of impulsivity, restlessness, emotional lability, and hot temper who do not suffer from schizophrenia or major mood disorder and do not have symptoms of schizotypal or borderline personality disorders.
Journal ArticleDOI
A double-blind, randomized, crossover trial of pemoline in fatigue associated with multiple sclerosis.
TL;DR: Pemoline may be an effective short-term treatment for fatigue associated with MS, but its adverse effects are not well tolerated by many patients.
Journal ArticleDOI
Stimulant treatment for the neurobehavioural sequelae of traumatic brain injury
Gualtieri Ct,Evans Rw +1 more
TL;DR: The results support the idea that at least some symptomatic improvement may be gained from low-dose stimulant treatment, although the statistical analysis of the data was compromised by the occurrence of carryover effects from one drug condition to another.
Journal ArticleDOI
Neuropsychological effects of methylphenidate in patients receiving a continuous infusion of narcotics for cancer pain
TL;DR: It is suggested that methylphenidate is capable of improving cognitive function in patients receiving high doses of opiates subcutaneously and more research is necessary in order to determine the duration of cognitive improvement after each dose ofethylphenidate as well as the best type and dose of amphetamine.