Journal ArticleDOI
Mediterranean diet and cardiovascular risk factors: a systematic review.
Giuseppe Grosso,Antonio Mistretta,Alessandro Frigiola,Salvatore Gruttadauria,Antonio Biondi,Francesco Basile,Paola Vitaglione,Nicolantonio D'Orazio,Fabio Galvano +8 more
TLDR
Most of the studies showed favorable effects of MD on CVD, although a certain degree of controversy remains in the respect of some issues, as obesity.Abstract:
The aim of this paper was to systematically review and analyze the epidemiological evidence on the role of Mediterranean diet (MD) in the prevention of cardiovascular diseases (CVD). Fifty-eight studies exploring the relation between MD and lipoprotein concentration, antioxidative capacity and inflammatory markers, hypertension, obesity, diabetes, and metabolic syndrome, were identified and selected. These included 33 cross-sectional, 9 cohort, and 16 intervention studies. Most of the studies showed favorable effects of MD on CVD, although a certain degree of controversy remains in the respect of some issues, as obesity. Important methodological differences and limitations in the studies make difficult to compare results, thus further studies, particularly randomized clinical trials, are needed to finally substantiate the benefits of MD and to shed some lights on mechanisms.read more
Citations
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Journal ArticleDOI
Treatment of NAFLD with diet, physical activity and exercise
TL;DR: Clinical evidence strongly supports the role of lifestyle modification as a primary therapy for the management of NAFLD and NASH and should be accompanied by the implementation of strategies to avoid relapse and weight regain.
Journal ArticleDOI
Benefits of the Mediterranean Diet: Insights From the PREDIMED Study
Miguel Ángel Martínez-González,Miguel Ángel Martínez-González,Jordi Salas-Salvadó,Ramon Estruch,Dolores Corella,Montse Fitó,Emilio Ros,Predimed Study Investigators +7 more
TL;DR: The PREDIMED trial provided strong evidence that a vegetable-based MeDiet rich in unsaturated fat and polyphenols can be a sustainable and ideal model for CVD prevention.
Journal ArticleDOI
The Mediterranean Diet and Cardiovascular Health.
Miguel Ángel Martínez-González,Miguel Ángel Martínez-González,Miguel Ángel Martínez-González,Alfredo Gea,Alfredo Gea,Miguel Ruiz-Canela,Miguel Ruiz-Canela +6 more
TL;DR: Criteria for causality was met, potential sources of controversies did not represent any reason to compromise the main findings of the available observational studies and randomized controlled trials, and the available evidence is large, strong, and consistent.
Journal ArticleDOI
Food based dietary patterns and chronic disease prevention
Matthias B. Schulze,Miguel Ángel Martínez-González,Miguel Ángel Martínez-González,Miguel Ángel Martínez-González,Teresa T. Fung,Teresa T. Fung,Alice H. Lichtenstein,Nita G. Forouhi +7 more
TL;DR: Current knowledge on the associations between dietary patterns and cancer, coronary heart disease, stroke, and type 2 diabetes is discussed, focusing on areas of uncertainty and future research directions.
Journal ArticleDOI
A comprehensive meta-analysis on evidence of Mediterranean diet and cardiovascular disease: Are individual components equal?
Giuseppe Grosso,Stefano Marventano,Justin Yang,Agnieszka Micek,Andrzej Pajak,Luca Scalfi,Fabio Galvano,Stephen Nicholas Kales +7 more
TL;DR: A meta-analysis of prospective studies and randomized control trials between Mediterranean diet adherence and CVD incidence and mortality revealed that the protective effects of the diet appear to be most attributable to olive oil, fruits, vegetables, and legumes.
References
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