Journal ArticleDOI
Melatonin secretion in children with epilepsy
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TLDR
There were no associations between MLT secretion/excretion parameters (diurnal profile, peak nocturnal concentrations, area under the time curve, duration of elevated concentrations, acrophase) and seizure characteristics (time, type of seizures, antiepileptic medications).About:
This article is published in Epilepsy & Behavior.The article was published on 2012-11-01. It has received 15 citations till now. The article focuses on the topics: Epilepsy & Melatonin.read more
Citations
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Journal ArticleDOI
Oxidative stress in epilepsy.
TL;DR: There is great need for clinical trials to evaluate new antioxidant compounds specifically on epileptic patients, and definitive evidence about the neuroprotective ability of the existing compounds is still lacking.
Journal ArticleDOI
Potential safety issues in the use of the hormone melatonin in paediatrics
TL;DR: Melatonin is a hormone produced by the pineal gland during the night in response to light/dark information received by the retina and its integration by the suprachiasmatic nucleus.
Journal ArticleDOI
Melatonin-Measurement Methods and the Factors Modifying the Results. A Systematic Review of the Literature.
TL;DR: The aim of the study was to compare methods and conditions of determinations carried out with the identification of factors potentially affecting the measurements obtained, and identified a group of modifiable and unmodifiable factors that facilitate data interpretation.
Journal Article
Delayed sleep phase syndrome
TL;DR: Most children and adolescents with DSPS describe themselves as “night owls” and usually feel and function their best in the evening and nighttime hours, and usually get much less sleep on weekdays than on weekends or holidays.
Journal ArticleDOI
Melatonin as a Novel Interventional Candidate for Fragile X Syndrome with Autism Spectrum Disorder in Humans
Jinyoung Won,Yunho Jin,Jeonghyun Choi,Sookyoung Park,Sookyoung Park,Tae Ho Lee,Sang-Rae Lee,Kyu-Tae Chang,Yonggeun Hong +8 more
TL;DR: Melatonin may be a useful treatment for FXS with ASD in terms of alleviating the adverse effects of variations in the circadian rhythm, and the neuroprotective effects of melatonin intervention therapies are discussed.
References
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Journal ArticleDOI
Variations in pattern of pubertal changes in girls.
W. A. Marshall,James M. Tanner +1 more
TL;DR: The extent of normal individual variation observed in the events of puberty among the girls of the Harpenden Growth Study is described.
Journal ArticleDOI
Variations in the Pattern of Pubertal Changes in Boys
W. A. Marshall,James M. Tanner +1 more
TL;DR: Mixed longitudinal data on the physical changes at puberty in 228 normal boys are presented together with normal standards for stages of genital and pubic hair development, finding that boys' genitalia begin to develop only about 6 months later than the girls' breasts and Pubic hair appears about 1½ years later in boys than in girls.
Journal ArticleDOI
A proposed diagnostic scheme for people with epileptic seizures and with epilepsy: report of the ILAE Task Force on Classification and Terminology.
TL;DR: A diagnostic scheme that makes use of standardized terminology and concepts to describe individual patients is proposed, and a variety of approaches to classification are possible, and some are presented here by way of example only.
Journal ArticleDOI
Variations in pattern of pubertal changes in girls
TL;DR: The extent of normal individual variation observed in the events of puberty among the girls of the Harpenden Growth Study is described.
Journal ArticleDOI
Sensitivity of the human circadian pacemaker to nocturnal light: melatonin phase resetting and suppression
Jamie M. Zeitzer,Jamie M. Zeitzer,Derk-Jan Dijk,Richard E. Kronauer,Richard E. Kronauer,Richard E. Kronauer,Emery N. Brown,Emery N. Brown,Emery N. Brown,Charles A. Czeisler,Charles A. Czeisler,Charles A. Czeisler +11 more
TL;DR: It is demonstrated that humans are highly responsive to the phase‐delaying effects of light during the early biological night and that both the phase resetting response to light and the acute suppressive effect of light on plasma melatonin follow a logistic dose‐response curve, as do many circadian responses to light in mammals.