Membrane ultrastructure at mammalian intercellular junctions
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This article is published in Progress in Biophysics & Molecular Biology.The article was published on 1973-01-01 and is currently open access. It has received 498 citations till now. The article focuses on the topics: Ultrastructure & Cell junction.read more
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Book ChapterDOI
Structure and function of intercellular junctions.
TL;DR: This chapter reviews the morphological information on intercellular junctions derived from thin-sectioning, negative staining and freeze-cleave techniques, as well as from x-ray diffraction and biochemical investigations, and correlates the structural parameters with known or proposed physiological functions.
Journal ArticleDOI
Structural basis of cell-cell adhesion by cadherins.
Lawrence Shapiro,Allison M. Fannon,Peter D. Kwong,Andrew J. Thompson,Mogens S. Lehmann,Gerhard Grübel,Jean-François Legrand,Jean-François Legrand,Jens Als-Nielsen,Jens Als-Nielsen,David R. Colman,Wayne A. Hendrickson +11 more
TL;DR: A linear zipper of molecules that mirrors the linear structure of the intracellular filaments with which cadherins associate may provide a mechanism to marshal individual molecular adhesive interactions into strong bonds between cells.
Journal ArticleDOI
Transmembrane control of the receptors on normal and tumor cells: I. Cytoplasmic influence over cell surface components☆
Journal ArticleDOI
Barrier function of epithelia
TL;DR: An important role for active Na+ transport in the maintenance of the epithelial barrier function can be postulated after extensive electrophysiological and morphological work done in recent years.
References
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Journal ArticleDOI
Junctional complexes in various epithelia
TL;DR: The tight junction is impervious to concentrated protein solutions and appears to function as a diffusion barrier or "seal," and the desmosome and probably also the zonula adhaerens may represent intercellular attachment devices.
Journal ArticleDOI
Fine structural localization of a blood-brain barrier to exogenous peroxidase
TL;DR: These findings localize, at a fine structural level, a "barrier" to the passage of peroxidase at the endothelium of vessels in the cerebral cortex in mice, particularly with reference to a recent study in which similar techniques were applied to capillaries in heart and skeletal muscle.
Journal ArticleDOI
Junctions between intimately apposed cell membranes in the vertebrate brain
TL;DR: Endothelial and epithelial tight junctions occlude the interspaces between blood and parenchyma or cerebral ventricles, thereby constituting a structural basis for the blood-brain and blood-cerebrospinal fluid barriers.
Journal ArticleDOI
The Fine Structure of the Nervous System.
TL;DR: This is the first atlas of the ultrastructure of the mature nervous system and it is a relatively complete collection of elegant micrographs with an accompanying text that explores the role that thin astrocytic processes may play in isolating receptive surfaces, thereby preventing axon terminals from influencing.