Mercury Toxicity and Treatment: A Review of the Literature
Robin Bernhoft
TLDR
D diagnosis of mercury toxicity can be challenging but can be obtained with reasonable reliability and effective therapies for clinical toxicity have been described.Abstract:
Mercury is a toxic heavy metal which is widely dispersed in nature. Most human exposure results from fish consumption or dental amalgam. Mercury occurs in several chemical forms, with complex pharmacokinetics. Mercury is capable of inducing a wide range of clinical presentations. Diagnosis of mercury toxicity can be challenging but can be obtained with reasonable reliability. Effective therapies for clinical toxicity have been described.read more
Citations
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Journal ArticleDOI
The Pharmacological Basis of Therapeutics
TL;DR: The Pharmacological Basis of Therapeutics, by Prof. Louis Goodman and Prof. Alfred Gilman, New York: The Macmillan Company, 1941, p.
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Heavy metal pollution in the environment and their toxicological effects on humans
TL;DR: The physiological and biochemical effects of each heavy metal bioaccumulation in humans and the level of gravity and disquieting factor of the disease are shown.
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The relative impact of toxic heavy metals (THMs) (arsenic (As), cadmium (Cd), chromium (Cr)(VI), mercury (Hg), and lead (Pb)) on the total environment: an overview.
Zeeshanur Rahman,Ved Pal Singh +1 more
TL;DR: This review provides a comprehensive account of the relative impact of the THMs As, Cd, Cr(VI), Hg, and Pb on the authors' total environment.
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Toxic Mechanisms of Five Heavy Metals: Mercury, Lead, Chromium, Cadmium, and Arsenic.
TL;DR: In this paper, the authors reviewed the mechanistic action of heavy metals according to the available animal and human studies and found similar pathways for these metals to induce toxicity including ROS generation, weakening of the antioxidant defense, enzyme inactivation, and oxidative stress.
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Cadmium Toxicity and Treatment
TL;DR: Detoxification of cadmium with EDTA and other chelators is possible and has been shown to be therapeutically beneficial in humans and animals when done using established protocols.
References
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Book
The pharmacological basis of therapeutics
TL;DR: In this article, 42 authors share the herculean task of reviewing the flood of recent literature on pharmacology and rational use of drugs, under single or dual authorship they contribute the 76 chapters in the 18 sections.
Journal ArticleDOI
The burden of oral disease: challenges to improving oral health in the 21st century.
TL;DR: The incidence of dental caries will increase in the near future in many developing countries of Africa, as a result of growing consumption of sugars and inadequate exposure to fluorides, and the risk of periodontal disease and tooth loss may increase.
Book
Handbook on the toxicology of metals
TL;DR: Handbook of the Toxicology of Metals as discussed by the authors is the standard reference work for physicians, toxicologists and engineers in the field of environmental and occupational health, which is a comprehensive review of the effects on biological systems from metallic elements and compounds.
Journal ArticleDOI
The Pharmacological Basis of Therapeutics
TL;DR: The Pharmacological Basis of Therapeutics, by Prof. Louis Goodman and Prof. Alfred Gilman, New York: The Macmillan Company, 1941, p.
Journal ArticleDOI
Cognitive Deficit in 7-year-old Children With Prenatal Exposure to Methylmercury
Philippe Grandjean,Pal Weihe,Roberta F. White,Roberta F. White,Roberta F. White,Frodi Debes,Shunichi Araki,Kazuhito Yokoyama,Katsuyuki Murata,Nicolina Sørensen,Rasmus Dahl,Poul J. Jørgensen +11 more
TL;DR: The effects on brain function associated with prenatal methylmercury exposure therefore appear widespread, and early dysfunction is detectable at exposure levels currently considered safe.