Cadmium Toxicity and Treatment
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TLDR
Detoxification of cadmium with EDTA and other chelators is possible and has been shown to be therapeutically beneficial in humans and animals when done using established protocols.Abstract:
Cadmium is a heavy metal of considerable toxicity with destructive impact on most organ systems. It is widely distributed in humans, the chief sources of contamination being cigarette smoke, welding, and contaminated food and beverages. Toxic impacts are discussed and appear to be proportional to body burden of cadmium. Detoxification of cadmium with EDTA and other chelators is possible and has been shown to be therapeutically beneficial in humans and animals when done using established protocols.read more
Citations
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Journal ArticleDOI
The Effects of Cadmium Toxicity
Giuseppe Genchi,Maria Stefania Sinicropi,Graziantonio Lauria,Alessia Carocci,Alessia Catalano +4 more
TL;DR: Recent studies show that cadmium induces various epigenetic changes in mammalian cells, both in vivo and in vitro, causing pathogenic risks and the development of various types of cancers.
Journal ArticleDOI
Cadmium toxicity and treatment: An update.
TL;DR: Patients with cadmium toxicity need gastrointestinal tract irrigation, supportive care, and chemical decontamination traditional-based chelation therapy with appropriate new chelating agents and nanoparticle-based antidotes.
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Protective effect of curcumin against heavy metals-induced liver damage.
TL;DR: Curcumin reduces the hepatotoxicity induced by arsenic, cadmium, chromium, copper, lead and mercury, prevents histological injury, lipid peroxidation and glutathione (GSH) depletion, maintains the liver antioxidant enzyme status and protects against mitochondrial dysfunction.
Journal ArticleDOI
Heavy metal toxicity: An update of chelating therapeutic strategies
TL;DR: Heavy metal poisoning is a common health problem because of mining, smelting, industrial, agricultural and sewage waste, but it can be efficiently excreted from the body following treatment with proper chelation agents.
Journal ArticleDOI
Protective effects of flavonoids against microbes and toxins: The cases of hesperidin and hesperetin.
TL;DR: The protective activities of Hesperidin and Hst against microbes and several toxicities induced by oxidants, chemicals, toxins, chemotherapy and radiotherapy agents, which were reported in vitro and in vivo are discussed.
References
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TL;DR: A comprehensive account of recent developments in the research on heavy metal poisoning particularly the role of oxidative stress/free radicals in the toxic manifestation is attempted, an update about the recent strategies for the treatment with chelating agents and a possible beneficial role of antioxidants supplementation to achieve the optimum effects are attempted.