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neutrophil function The mechanism and impact of thrombospondin-4 polymorphisms on

Elzbieta Pluskota, +5 more
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The article was published on 2013-01-01 and is currently open access. It has received 0 citations till now. The article focuses on the topics: Thrombospondin 4.

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Inflammation in atherosclerosis

Peter Libby
- 19 Dec 2002 - 
TL;DR: The new appreciation of the role of inflammation in atherosclerosis provides a mechanistic framework for understanding the clinical benefits of lipid-lowering therapies and unravelling the details of inflammatory pathways may eventually furnish new therapeutic targets.
Journal ArticleDOI

Endothelial Dysfunction in Cardiovascular Diseases: The Role of Oxidant Stress

Hua Cai, +1 more
- 10 Nov 2000 - 
TL;DR: Accumulating evidence suggests that oxidant stress alters many functions of the endothelium, including modulation of vasomotor tone, and as the role of these various enzyme sources of ROS become clear, it will perhaps be possible to use more specific therapies to prevent their production and ultimately correct endothelial dysfunction.
Journal ArticleDOI

Mammalian Mitogen-Activated Protein Kinase Signal Transduction Pathways Activated by Stress and Inflammation

John M. Kyriakis, +1 more
- 01 Apr 2001 - 
TL;DR: This review focuses on the biochemical components and regulation of mammalian stress-regulated mitogen-activated protein kinase (MAPK) pathways, and the nuclear factor-kappa B pathway, a second stress signaling paradigm.
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A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins.

John Rouse, +7 more
- 23 Sep 1994 - 
TL;DR: The RKK, RK, and MAPKAP kinase-2 constitute a new stress-activated signal transduction pathway in vertebrates that is distinct from the classical MAPK cascade.
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MAP Kinases in the Immune Response

Chen Dong, +2 more
- 01 Jan 2002 - 
TL;DR: Recent progress in understanding the function and regulation of MAP kinase pathways in these phases of immune responses in mammalian species is summarized.