Journal ArticleDOI
New ligands double the scope of the catalytic asymmetric dihydroxylation of olefins
K. Barry Sharpless,Willi Amberg,Matthias Beller,Hou Chen,Jens Hartung,Yasuhiro Kawanami,Doris Lubben,Eric Manoury,Yasukazu Ogino,Tomoyuki Shibata,Tatsuzo Ukita +10 more
Reads0
Chats0
TLDR
Improved ligands render terminal olefins good substrates for the osmium-catalyzed asymmetric dihydroxylation (ADH) process as discussed by the authors.Abstract:
Improved ligands render terminal olefins good substrates for the osmium-catalyzed asymmetric dihydroxylation (ADH) process, and the amounts of chiral ligand and osmium catalyst required diminish dramaticallyread more
Citations
More filters
Journal ArticleDOI
The first synthesis of vancomycinic acid
TL;DR: Vancomycinic Acid moiety (C, D and E rings) 2 of vancomYcin is synthesised making efficient use of the ease of nucleophilic displacements of halides on 2,6-dibromobenzoquinone followed by a diastereoselective elaboration of the quinone unit to aryl glycine.
Journal ArticleDOI
Katalytische Oxidation teil‐ und vollfluorierter Olefine mit Osmiumtetraoxid
Chemistry and Biology of Cinchona Alkaloids 21
TL;DR: Cinchona alkaloids comprising quinine, quinidine, cinchonidine, and Cinchonine as the major members constitute a unique class of quinoline alkaloid with tremendous impact on human civilization as mentioned in this paper.
Book ChapterDOI
Proanthocyanidins: Chemistry and Biology
TL;DR: In this article, the authors summarized progress in the chemistry and biology of the proanthocyanidins, a diverse group of naturally occurring plant polyphenols, emphasizing results emanating from studies in the post-CONAP-I era.
Journal ArticleDOI
Diastereocontrol in the asymmetric dihydroxylation of chiral 3-alkenyl-4,5-dihydroisoxazoles
TL;DR: In this paper, the authors show that, in the case of catalytic asymmetric dihydroxylation of 4, one diastereomer was heavily predominant with (DHQ)2-PHAL as the chiral auxiliary (mismatched pair; 90% d.e.
References
More filters
Journal ArticleDOI
Nuclear magnetic resonance enantiomer regents. Configurational correlations via nuclear magnetic resonance chemical shifts of diastereomeric mandelate, O-methylmandelate, and .alpha.-methoxy-.alpha.-trifluoromethylphenylacetate (MTPA) esters
James A. Dale,Harry S. Mosher +1 more
PatentDOI
First practical method for asymmetric epoxidation
Tsutomu Katsuki,K. B. Sharpless +1 more
TL;DR: In this article, a metal alkoxide is used as a catalyst, where the metal has a coordination number of at least four, and at least one, usually two, of the alkoxide groups bonded to the metal are bonded to asymmetric carbon atoms.
Journal ArticleDOI
Asymmetric dihydroxylation via ligand-accelerated catalysis
TL;DR: Dihydroxylation asymetrique de composes ethyleniques du type styrene, vinylcyclohexane, hexene-3 en les glycols correspondants as mentioned in this paper.
Journal ArticleDOI
Asymmetric induction in the reaction of osmium tetroxide with olefins
Journal ArticleDOI
An improved synthesis of the taxol side chain and of RP 56976
TL;DR: In this paper, the methode presentee se fait au depart de phenyl-3 dihydroxy-2,3 propionate de methyle via epoxydation, et d'azoture de sodium.