Journal ArticleDOI
Nifedipine: Differential pulse polarography and photodecomposition.
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TLDR
In this article, a method for the differential-pulse polarographic determination of nifedipine has been developed, based on the electrochemistry of the aromatic nitro group in the drug.About:
This article is published in Talanta.The article was published on 1989-03-01. It has received 41 citations till now. The article focuses on the topics: Ultraviolet light & Polarography.read more
Citations
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Determination of nifedipine using nanostructured electrochemical sensor based on simple synthesis of Ag nanoparticles at the surface of glassy carbon electrode: Application to the analysis of some real samples
TL;DR: In this article, the catalytic activity of nifedipine (NID) was studied at the surface of a modified electrode which prepared by immobilization of Ag nanoparticles (AgNPs) at a glassy carbon electrode.
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Antioxidant Effects of 1,4-Dihydropyridine and Nitroso Aryl Derivatives on the Fe+3/Ascorbate-Stimulated Lipid Peroxidation in Rat Brain Slices
Guillermo Díaz-Araya,L. Godoy,L. Naranjo,A. Squella,María Eugenia Letelier,Luis J. Núñez-Vergara +5 more
TL;DR: All the tested nitroso aryl derivatives were more potent inhibitors of lipid peroxidation than were the parent nitro compounds, and the rank order of antioxidant potency for these derivatives can be established as: ortho-nitrosotoluene>NTP>nitrosobenzene.
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Cyclic voltammetric study of some calcium antagonist dihydropyridines in aqueous medium
TL;DR: In this article, the electrochemical behavior of dihydropyridine analogues was investigated in aqueous buffered solution using a glassy carbon electrode, and a general EC mechanism was proposed for the overall process.
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Extractive spectrophotometric methods for the determination of nifedipine in pharmaceutical formulations using bromocresol green, bromophenol blue, bromothymol blue and eriochrome black T.
TL;DR: Four simple, sensitive and accurate spectrophotometric methods have been developed for the determination of nifedipine in pharmaceutical formulations and shows excellent agreement and indicates no significant difference in accuracy and precision.
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Voltammetric determination of nifedipine using a β-cyclodextrin modified multi-walled carbon nanotube paste electrode
TL;DR: An electrochemical method employing a β-cyclodextrin modified carbon nanotube paste electrode (βCD-CNT-PE) has been developed for the determination of nifedipine (NIF) as mentioned in this paper.
References
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Comparative pharmacology of calcium antagonists: Nifedipine, verapamil and diltiazem
TL;DR: Nifedipine is a potent, long-acting vasodilator that has proved highly efficacious in relieving anginal symptoms caused by coronary vasospasm, and its value as an antiarrhythmic agent remains to be delineated.
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Calcium Channel Blocking Agents in the Treatment of Cardiovascular Disorders. Part II: Hemodynamic Effects and Clinical Applications
TL;DR: The negative inotropic effects of verapamil are valuable in improving the symptoms and hemodynamic disturbances of hypertrophic cardiomyopathy and the role of these agents in treating arterial hypertension, unstable angina pectoris, acute myocardial infarction, and ischemia during cardiopulmonary bypass needs to be determined.
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High-performance liquid chromatography of nifedipine, its metabolites and photochemical degradation products.
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Determination of Nifedipine in Plasma by High-Performance Liquid Chromatography
TL;DR: A simple high-performance liquid chromatographic method permits the accurate determination of the drug in plasma at concentrations as low as 2 ng/ml and is suitable for drug monitoring and for investigation of the bioavailabilities of drug preparations.