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Open AccessJournal ArticleDOI

Nuclear Medicine Imaging in Pediatric Neurology.

TLDR
In pediatric patients with brain tumors, nuclear medicine imaging can be clinically helpful in the diagnosis, directing biopsy, planning therapy, differentiating tumor recurrence from post-treatment sequelae, and assessment of response to therapy.
Abstract
Nuclear medicine imaging can provide important complementary information in the management of pediatric patients with neurological diseases. Pre-surgical localization of the epileptogenic focus in medically refractory epilepsy patients is the most common indication for nuclear medicine imaging in pediatric neurology. In patients with temporal lobe epilepsy, nuclear medicine imaging is particularly useful when magnetic resonance imaging findings are normal or its findings are discordant with electroencephalogram findings. In pediatric patients with brain tumors, nuclear medicine imaging can be clinically helpful in the diagnosis, directing biopsy, planning therapy, differentiating tumor recurrence from post-treatment sequelae, and assessment of response to therapy. Among other neurological diseases in which nuclear medicine has proved to be useful are patients with head trauma, inflammatory-infectious diseases and hypoxic-ischemic encephalopathy.

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Journal ArticleDOI

Nuclear Medicine Theranostics: Perspective from Pakistan.

TL;DR: A perspective on theranostics from Pakistan is presented, showing a new found impetus to the use of pairs of radiopharmaceuticals for diagnosis and treatment.
Journal ArticleDOI

Obrazowanie radioizotopowe w onkologii pediatrycznej – przegląd metod

TL;DR: The most common malignancies observed in paediatric patients are leukemia, lymphoma, central nervous system (CNS) malignant neoplasms and neuroblastoma, suggesting the necessity to include the advanced imaging procedures into clinical management.
Book ChapterDOI

Imaging Modalities: Nuclear Medicine

TL;DR: Technical aspects include distribution of the radiotracer during the time of image collection, half-life, energy of emission, type of radiation, tracer kinetics, production of radionuclides, data analysis, appropriate patient preparation, and standardized acquisition protocols.
References
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Journal ArticleDOI

A Critical Period of Brain Development: Studies of Cerebral Glucose Utilization with PET

TL;DR: The measurement of absolute rates of glucose utilization during development indicates that the cerebral cortex undergoes a dynamic course of metabolic maturation that persists until ages 16-18 years, at which time the child's cerebral cortex uses over twice as much glucose as that of adults.
Journal ArticleDOI

Subtraction ictal SPECT co-registered to MRI improves clinical usefulness of SPECT in localizing the surgical seizure focus

TL;DR: It is concluded that SISCOM improves the sensitivity and the specificity of SPECT in localizing the seizure focus for epilepsy surgery and is predictive of postsurgical improvement in seizure outcome.
Journal ArticleDOI

EANM procedure guidelines for PET brain imaging using [(18)F]FDG : version 2

TL;DR: These guidelines summarize the current views of the European Association of Nuclear Medicine Neuroimaging Committee and includes an update in the light of advances in PET technology, the introduction of hybrid PET/CT systems and the broadening clinical indications for FDG brain imaging.
Journal ArticleDOI

Surgical outcome and prognostic factors of cryptogenic neocortical epilepsy.

TL;DR: Evaluated surgical outcomes and possible prognostic factors including the results of various diagnostic tools found Concordance with two or more presurgical evaluations was significantly related to a seizure‐free outcome.
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