K
Koen Van Laere
Researcher at Katholieke Universiteit Leuven
Publications - 414
Citations - 15732
Koen Van Laere is an academic researcher from Katholieke Universiteit Leuven. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 61, co-authored 371 publications receiving 13277 citations. Previous affiliations of Koen Van Laere include Ghent University Hospital.
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Journal ArticleDOI
18F-flutemetamol amyloid imaging in Alzheimer disease and mild cognitive impairment : a phase 2 trial.
Rik Vandenberghe,Rik Vandenberghe,Koen Van Laere,Adrian Ivanoiu,Eric Salmon,Christine Bastin,Eric Triau,Steen G. Hasselbalch,Ian Law,Allan R. Andersen,Alex Korner,Lennart Minthon,Gaëtan Garraux,Natalie Nelissen,Guy Bormans,Christopher Buckley,Rikard Owenius,Lennart Thurfjell,Gill Farrar,David J. Brooks,David J. Brooks +20 more
TL;DR: Validation of the 18F‐labeled PIB derivative18F‐flutemetamol could significantly enhance access to in vivo β‐amyloid imaging technology.
Journal ArticleDOI
Prevalence of amyloid PET positivity in dementia syndromes: a meta-analysis.
Rik Ossenkoppele,Willemijn J. Jansen,Gil D. Rabinovici,Dirk L. Knol,Wiesje M. van der Flier,Bart N.M. van Berckel,Philip Scheltens,Pieter Jelle Visser,Sander C.J. Verfaillie,Marissa D. Zwan,Sofie Adriaanse,Adriaan A. Lammertsma,Frederik Barkhof,William J. Jagust,Bruce L. Miller,Howard J. Rosen,Susan M. Landau,Victor L. Villemagne,Christopher C. Rowe,Dong Y. Lee,Duk L. Na,Sang W. Seo,Marie Sarazin,Catherine M. Roe,Osama Sabri,Henryk Barthel,Norman Koglin,John R. Hodges,Cristian E. Leyton,Rik Vandenberghe,Koen Van Laere,Alexander Drzezga,Stefan Förster,Timo Grimmer,Pascual Sánchez-Juan,José M. Carril,Vincent Mok,Vincent Camus,William E. Klunk,Ann D. Cohen,Philipp T. Meyer,Sabine Hellwig,Andrew B. Newberg,Kristian Steen Frederiksen,Adam S. Fleisher,Mark A. Mintun,David A. Wolk,Agneta Nordberg,Juha O. Rinne,Gaël Chételat,Alberto Lleó,Rafael Blesa,Juan Fortea,Karine Madsen,Karen M. Rodrigue,David J. Brooks +55 more
TL;DR: Findings indicate the potential clinical utility of amyloid imaging for differential diagnosis in early-onset dementia and to support the clinical diagnosis of participants with AD dementia and noncarrier APOE ε4 status.
Journal ArticleDOI
EANM procedure guidelines for PET brain imaging using [(18)F]FDG : version 2
Andrea Varrone,Susanne Asenbaum,Thierry Vander Borght,Jan Booij,Flavio Nobili,Kjell Någren,Jacques Darcourt,Özlem L. Kapucu,Klaus Tatsch,Peter Bartenstein,Koen Van Laere +10 more
TL;DR: These guidelines summarize the current views of the European Association of Nuclear Medicine Neuroimaging Committee and includes an update in the light of advances in PET technology, the introduction of hybrid PET/CT systems and the broadening clinical indications for FDG brain imaging.
Prevalence of Amyloid PET Positivity in Dementia Syndromes
Rik Ossenkoppele,Willemijn J. Jansen,Gil D. Rabinovici,Dirk L. Knol,Wiesje M. van der Flier,Bart N.M. van Berckel,Philip Scheltens,Pieter Jelle Visser,Sander C.J. Verfaillie,Marissa D. Zwan,Sofie Adriaanse,Adriaan A. Lammertsma,Frederik Barkhof,William J. Jagust,Bruce L. Miller,Howard J. Rosen,Susan M. Landau,Victor L. Villemagne,Christopher C. Rowe,Dong Y. Lee,Duk L. Na,Sang W. Seo,Marie Sarazin,Catherine M. Roe,Osama Sabri,Henryk Barthel,Norman Koglin,John R. Hodges,Cristian E. Leyton,Rik Vandenberghe,Koen Van Laere,Alexander Drzezga,Stefan Förster,Timo Grimmer,Pascual Sánchez-Juan,José M. Carril,Vincent Mok,Vincent Camus,William E. Klunk,Ann D. Cohen,Philipp T. Meyer,Sabine Hellwig,Andrew B. Newberg,Kristian Steen Frederiksen,Adam S. Fleisher,Mark A. Mintun,David A. Wolk,Agneta Nordberg,Juha O. Rinne,Gaël Chételat,Alberto Lleó,Rafael Blesa,Juan Fortea,Karine Madsen,Karen M. Rodrigue,David J. Brooks +55 more
Journal ArticleDOI
[18F]MK-9470, a positron emission tomography (PET) tracer for in vivo human PET brain imaging of the cannabinoid-1 receptor
H. Donald Burns,Koen Van Laere,Sandra M. Sanabria-Bohórquez,Terence G. Hamill,Guy Bormans,Wai-Si Eng,Ray E Gibson,Christine E. Ryan,Brett Connolly,Shil Patel,Stephen Krause,Amy Vanko,Anne Van Hecken,Patrick Dupont,Inge De Lepeleire,Paul Rothenberg,S. Aubrey Stoch,Josee Cote,William K. Hagmann,James P. Jewell,Linus S. Lin,Ping Liu,Mark T. Goulet,Keith Gottesdiener,John A. Wagner,Jan de Hoon,Luc Mortelmans,Tung M. Fong,Richard Hargreaves +28 more
TL;DR: Autoradiographic studies in rhesus monkey brain showed that [18F]MK-9470 binding is aligned with the reported distribution of CB1 receptors with high specific binding in the cerebral cortex, cerebellum, caudate/putamen, globus pallidus, substantia nigra, and hippocampus, and PET imaging studies in human research subject demonstrated behavior very similar to that seen in monkeys.