Journal ArticleDOI
Oka/Merck varicella vaccine in healthy children: final report of a 2-year efficacy study and 7-year follow-up studies.
Barbara J. Kuter,Robert E. Weibel,Robert E. Weibel,Harry A. Guess,Harry A. Guess,Holly Matthews,Holly Matthews,David H. Morton,David H. Morton,Beverly J. Neff,Beverly J. Neff,Philip J. Provost,Philip J. Provost,Barbara A. Watson,Barbara A. Watson,Stuart E. Starr,Stuart E. Starr,Stanley A. Plotkin,Stanley A. Plotkin +18 more
TLDR
A large double-blind, randomized, placebo-controlled trial of live attenuated Oka/Merck varicella vaccine was conducted among healthy children, 1-14 years of age, finding that the efficacy of the vaccine among susceptible children was 100%1.About:
This article is published in Vaccine.The article was published on 1991-09-01. It has received 195 citations till now. The article focuses on the topics: Varicella vaccine & Vaccination.read more
Citations
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Prevention of varicella: recommendations of the Advisory Committee on Immunization Practices (ACIP).
TL;DR: This report revises, updates, and replaces the 1996 and 1999 ACIP statements for prevention of varicella, and adopts new recommendations regarding the use of live, attenuated variceLLA vaccines for Prevention of Varicella.
Journal ArticleDOI
Varicella-zoster virus.
TL;DR: A live attenuated varicella vaccine (Oka/Merck strain) is now recommended for routine childhood immunization and passive antibody prophylaxis withvaricella-zoster immune globulin is indicated for susceptible high-risk patients exposed to variceella.
Journal ArticleDOI
Cost-effectiveness of a routine varicella vaccination program for US children
T A Lieu,Stephen L. Cochi,S B Black,M E Halloran,Henry R. Shinefield,Sandra J. Holmes,Melinda Wharton,A E Washington +7 more
TL;DR: A routine varicella vaccination program for healthy children would result in net savings from the societal perspective, which includes work-loss costs as well as medical costs, and would also be relatively cost-effective from the health care payer's perspective.
Journal ArticleDOI
Ten year follow-up of healthy children who received one or two injections of varicella vaccine.
Barbara J. Kuter,Holly Matthews,Henry R. Shinefield,Steve Black,Penelope H. Dennehy,Barbara Watson,Keith S. Reisinger,Lee Lian Kim,Lisa Lupinacci,Jonathan Hartzel,Ivan H. Chan +10 more
TL;DR: Administration of either one or two injections of varicella vaccine to healthy children results in long term protection against mostvaricella disease.
Journal ArticleDOI
The Effectiveness of the Varicella Vaccine in Clinical Practice
Marietta Vázquez,P. LaRussa,Anne A. Gershon,Sharon Steinberg,Kimberly Freudigman,Eugene D. Shapiro +5 more
TL;DR: The effectiveness of the varicella vaccine was virtually unchanged (87 percent) after adjustment for potential confounders by means of conditional logistic regression, indicating that the vaccine is highly effective as used in clinical practice.
References
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Book ChapterDOI
Nonparametric Estimation from Incomplete Observations
Edward L. Kaplan,Paul Meier +1 more
TL;DR: In this article, the product-limit (PL) estimator was proposed to estimate the proportion of items in the population whose lifetimes would exceed t (in the absence of such losses), without making any assumption about the form of the function P(t).
Journal ArticleDOI
Live attenuated varicella virus vaccine. Efficacy trial in healthy children.
Robert E. Weibel,B J Neff,Barbara J. Kuter,H A Guess,C A Rothenberger,A J Fitzgerald,K A Connor,A A McLean,Maurice R. Hilleman,Eugene B. Buynak +9 more
TL;DR: The live attenuated Oka/Merck varicella vaccine produced few clinical reactions and was well tolerated, and there was no clinical evidence of viral spread from vaccinated children to sibling controls.
Journal ArticleDOI
Modification of Chicken Pox in Family Contacts by Administration of Gamma Globulin
TL;DR: The need for a method of modification of chicken pox has become increasingly apparent, owing to the publication of descriptions of a variety of serious and sometimes fatal sequelae under certain well defined circumstances.
Journal ArticleDOI
Serologic response to varicella-zoster membrane antigens measured by direct immunofluorescence.
Journal Article
Varicella vaccine (VARIVAX) in healthy children and adolescents: results from clinical trials, 1987 to 1989.
C J White,Barbara J. Kuter,C S Hildebrand,K L Isganitis,Holly Matthews,W J Miller,Philip J. Provost,Ronald W. Ellis,Robert J. Gerety,Gary B. Calandra +9 more
TL;DR: Nearly all of the vaccinees who had varicella after vaccination had a clinically modified disease, and 99% of those tested maintained antibody at 1 year following vaccination.