Journal ArticleDOI
Optical diagnostics in urology: current applications and future prospects.
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This article is published in BJUI.The article was published on 2003-09-01. It has received 62 citations till now.read more
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Vibrational spectroscopy: a clinical tool for cancer diagnostics
Catherine Kendall,Martin Isabelle,Florian Bazant-Hegemark,Joanne Hutchings,Linda Orr,Jaspreet Babrah,Rebecca Baker,Nicholas Stone +7 more
TL;DR: This review summarises recent advances in vibrational spectroscopy and their impact on the diagnosis of cancer and illustrates the complementary advantage of using Raman and FTIR spectroscopic technologies together.
Journal ArticleDOI
Assessment of fiberoptic near-infrared raman spectroscopy for diagnosis of bladder and prostate cancer
TL;DR: In this paper, a fiberoptic Raman system was used to differentiate between benign and malignant bladder and prostate pathologic findings in vitro, and the prostate algorithm was able to differentiate benign samples (benign prostatic hyperplasia and prostatitis) from malignant samples (prostate cancer).
Journal ArticleDOI
The use of Raman spectroscopy to differentiate between different prostatic adenocarcinoma cell lines
TL;DR: RS shows promise for application in the diagnosis and grading of CaP in clinical practise as well as providing molecular information on CaP samples in a research setting.
Journal ArticleDOI
Prospects for laser-induced breakdown spectroscopy for biomedical applications: a review.
Vivek K. Singh,A. K. Rai +1 more
TL;DR: The unique abilities of LIBS including detection of molecular species and calibration-free LIBS are compared with those of other conventional techniques including atomic absorption spectroscopy, inductively coupled plasma atomic emission Spectroscopy and mass spectroscope, and X-ray fluorescence.
Journal ArticleDOI
Intraoperative near infrared fluorescence guided identification of the ureters using low dose methylene blue: a first in human experience.
Floris P. R. Verbeek,Joost R. van der Vorst,Boudewijn E. Schaafsma,Rutger-Jan Swijnenburg,Katja N. Gaarenstroom,Henk W. Elzevier,Cornelis J.H. van de Velde,John V. Frangioni,Alexander L. Vahrmeijer +8 more
TL;DR: This study demonstrates the first successful use of near infrared fluorescence using low dose methylene blue for the identification of the ureters during lower abdominal surgery.
References
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Journal ArticleDOI
5‐Aminolevulinic Acid‐Based Photodynamic Therapy: Principles and Experimental Research
TL;DR: Because PpIX is an efficient photosensitizer, ALA has been introduced as a drug for clinical photodynamic therapy (PDT) of cancer (8,9).
Journal ArticleDOI
Near‐infrared Raman spectroscopy for the classification of epithelial pre‐cancers and cancers
TL;DR: The use of near-infrared Raman spectroscopy to interrogate epithelial tissue biochemistry and hence distinguish between normal and abnormal tissues was investigated and principal component fed linear discriminant models demonstrated excellent group separation, when tested by cross-validation.
Journal ArticleDOI
Detection of Early Bladder Cancer by 5-Aminolevulinic Acid Induced Porphyrin Fluorescence
Martin Kriegmair,R. Baumgartner,Ruth Knüchel,Herbert Stepp,Ferdinand Hofstädter,Alfons Hofstetter +5 more
TL;DR: The sensitivity of detecting dysplasia or early bladder cancer can be improved by 5-aminolevulinic acid induced porphyrin fluorescence which is significantly greater than that of white light cystoscopy.
Journal ArticleDOI
Spectroscopic diagnosis of bladder cancer with elastic light scattering
Judith R. Mourant,Irving J. Bigio,James D. Boyer,Richard L. Conn,Tamara M. Johnson,Tsutomu Shimada +5 more
TL;DR: The goal of this study was to evaluate elastic scatter measurements as a tool for diagnosing bladder cancer by making in vivo measurements with the optical biopsy system developed at Los Alamos National Laboratory.
Journal ArticleDOI
Fluorescence photodetection of neoplastic urothelial lesions following intravesical instillation of 5-aminolevulinic acid
Martin Kriegmair,R. Baumgartner,R. Baumgartner,Ruth Knuechel,Ruth Knuechel,Pia Steinbach,Pia Steinbach,A. Ehsan,A. Ehsan,W. Lumper,W. Lumper,Ferdinand Hofstädter,Ferdinand Hofstädter,Alfons Hofstetter,Alfons Hofstetter +14 more
TL;DR: Labeling of urothelial lesions by PPIX fluorescence induced by intravesically instilled ALA seems to be a promising diagnostic procedure for malignant lesions that are difficult to visualize with standard cystoscopy.