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Optical topography: practical problems and new applications.

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TLDR
The optimum wavelength pair improved the S/N ratio sixfold for deoxyhemoglobin, and new configurations of light irradiation and detection positions doubled the spatial resolution in observations of higher-order brain functions.
Abstract
We will briefly review the present status of optical topography and then discuss the method of improving practicality, i.e., the signal-to-noise (S/N) ratio and the spatial resolution in observations of higher-order brain functions. The optimum wavelength pair improved the S/N ratio sixfold for deoxyhemoglobin, and new configurations of light irradiation and detection positions doubled the spatial resolution. We also report on developing application fields of optical topography. This modality will bridge the gap between natural sciences, neuroscience, and pedagogy, and show actual real-time brain activity.

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A brief review on the history of human functional near-infrared spectroscopy (fNIRS) development and fields of application.

TL;DR: A brief historical overview of the events that have shaped the present status of fNIRS is presented, including the introduction of the commercial multi-channel systems, recent commercial wireless instrumentation and more advanced prototypes.
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Recent advances in diffuse optical imaging.

TL;DR: The current state-of-the-art of diffuse optical imaging is reviewed, which is an emerging technique for functional imaging of biological tissue and recent work on in vivo applications including imaging the breast and brain is reviewed.
Journal ArticleDOI

Diffuse optical imaging of brain activation: approaches to optimizing image sensitivity, resolution, and accuracy.

TL;DR: Advances currently being made and issues to consider for improving optical image quality include the optimal selection of wavelengths to minimize random and systematic error propagation in the calculation of the hemoglobin concentrations.
Journal ArticleDOI

Virtual spatial registration of stand-alone fNIRS data to MNI space.

TL;DR: A novel registration method, based on simulations in place of physical measurements for optode positioning, that allowed the spatial registration of completely stand-alone fNIRS data onto MNI space without the use of supplementary measurements.
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Acute moderate exercise elicits increased dorsolateral prefrontal activation and improves cognitive performance with Stroop test.

TL;DR: Using multichannel functional near-infrared spectroscopy (fNIRS), this article found brain activation due to Stroop interference in the lateral prefrontal cortices in both hemispheres.
References
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Journal ArticleDOI

Noninvasive, infrared monitoring of cerebral and myocardial oxygen sufficiency and circulatory parameters

TL;DR: Observations by infrared transillumination in the exposed heart and in the brain in cephalo without surgical intervention show that oxygen sufficiency for cytochrome a,a3, function, changes in tissue blood volume, and the average hemoglobin-oxyhemoglobin equilibrium can be recorded effectively and in continuous fashion for research and clinical purposes.
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Estimation of optical pathlength through tissue from direct time of flight measurement

TL;DR: Monte Carlo modelling of light pulses in tissue has shown that the mean value of the time dispersed light pulse correlates with the pathlength used in quantitative spectroscopic calculations, and this result has been verified in a phantom material.
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Near infrared spectroscopy (NIRS) : a new tool to study hemodynamic changes during activation of brain function in human adults

TL;DR: NIRS is a simple bedside technique for the assessment of hemodynamic alterations accompanying brain activation using near infrared spectroscopy and it is demonstrated that these findings are not due to alterations in skin blood flow.
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Spatial and temporal analysis of human motor activity using noninvasive NIR topography

TL;DR: It was found that the regional change in cerebral blood volume in the primary motor area overlaps the global change around the motor cortex.
Journal ArticleDOI

Detection of dynamic changes in cerebral oxygenation coupled to neuronal function during mental work in man

TL;DR: In this paper, changes in the oxygenation state of brain hemoglobin during mental work were monitored in real time (time resolution: 1 s) using near-infrared spectrophotometry in 14 healthy volunteers.
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