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Journal ArticleDOI

Optimal Biased Weighing Designs and Two-Level Main-Effect Plans

TLDR
In this paper, the authors considered the problem of optimal biased chemical and spring balance weights for the case N ≡ 0 (mod 4), where N is the run size, and showed that for all p ≥ 0, there is a Φ p -optimal estimator for this problem.
Abstract
Optimal biased chemical and spring balance weighing designs are considered. Optimal designs in either setting can be obtained from those in the other via a simple transformation. Optimal approximate designs for unbiased chemical balance, biased chemical balance, and biased spring balance are closely related and can easily be obtained from one another. These designs correspond to universally optimal exact designs for the case N ≡ 0 (mod 4), where N is the run size. While Cheng's (1980) result on the type 1 optimality of certain unbiased chemical balance weighing designs for the case N ≡ 1 (mod 4) can be extended to the biased setting, such an extension does not hold for N ≡ 2 (mod 4). We obtain exact Φ p -optimal designs in the latter case for all p ≥ 0. The results obtained in this article can also be applied to optimal main-effect plans when one is interested in the main effects but not the general mean. Under the usual orthogonal parameterization, the model matrices of main-effect plans have 1, −1 entri...

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Citations
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Journal ArticleDOI

Optimal experimental designs for fMRI via circulant biased weighing designs

TL;DR: A general theory to guide the selection of fMRI designs for estimating a hemodynamic response function (HRF) that models the effect over time of the mental stimulus, and for studying the comparison of two HRFs is developed.
Journal ArticleDOI

Necessary and sufficient conditions in the problem of D-optimal weighing designs with autocorrelated errors

TL;DR: Nessary and sufficient conditions determining D-optimality of chemical balance weighing design with three objects are proved under first-order autoregressive errors with negative autocorrelation.
Journal ArticleDOI

Compromise designs under baseline parameterization

TL;DR: In this article, the authors examined a class of compromise designs obtained by adding runs to one-factor-at-a-time fractional factorial designs and developed a complete search algorithm to find optimal compromise designs.
Journal ArticleDOI

Optimal design of FMRI experiments using circulant (Almost-)orthogonal arrays

TL;DR: In this paper, the authors developed a theory that not only successfully explains the structure of a circulant design, but also provides a method of constructing efficient fMRI designs systematically.
Journal ArticleDOI

Regular E-Optimal Spring Balance Weighing Designs with Correlated Errors

TL;DR: In this paper, the maximal eigenvalue of the inverse of the information matrix of estimators is determined for an E-optimal spring balance weighting design with correlated errors.
References
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Book

Inequalities: Theory of Majorization and Its Applications

TL;DR: In this paper, Doubly Stochastic Matrices and Schur-Convex Functions are used to represent matrix functions in the context of matrix factorizations, compounds, direct products and M-matrices.
Journal ArticleDOI

Design issues for cDNA microarray experiments.

TL;DR: This paper focuses on microarray experiments, which are used to quantify and compare gene expression on a large scale and can be costly in terms of equipment, consumables and time.
Journal ArticleDOI

General Equivalence Theory for Optimum Designs (Approximate Theory)

J. Kiefer
- 01 Sep 1974 - 
TL;DR: For general optimality criteria, this article obtained criteria equivalent to $\Phi$-optimality under various conditions on ''Phi'' and showed that such equivalent criteria are useful for analytic or machine computation of ''phi''-optimum designs.