Origins of dengue type 2 viruses associated with increased pathogenicity in the Americas.
Rebeca Rico-Hesse,Lisa M. Harrison,Rosa Alba Salas,Duilia Tovar,Ananda Nisalak,Celso Ramos,Jorge Boshell,Maria Teresa R. de Mesa,Rita Maria Ribeiro Nogueira,Amelia P.A. Travassos Da Rosa +9 more
Reads0
Chats0
TLDR
Phylogenetic analyses suggest that these genotypes of dengue type 2 virus originated in Southeast Asia and that they displaced the native, American genotype in at least four countries, and vaccination and other control efforts should therefore be directed at decreasing the transmission of these "virulent" genotypes.About:
This article is published in Virology.The article was published on 1997-04-14 and is currently open access. It has received 676 citations till now. The article focuses on the topics: Dengue virus & Dengue fever.read more
Citations
More filters
Journal ArticleDOI
Dengue and Dengue Hemorrhagic Fever
TL;DR: A review of the changing epidemiology of dengue and hemorrhagic fever by geographic region, the natural history and transmission cycles, clinical diagnosis of both Dengue fever and DVF, serologic and virologic laboratory diagnoses, pathogenesis, surveillance, prevention, and control can be found in this paper.
Dengue and dengue hemorrhagic fever.
TL;DR: A major challenge for public health officials in all tropical areas of the world is to devleop and implement sustainable prevention and control programs that will reverse the trend of emergent dengue hemorrhagic fever.
Journal ArticleDOI
Dengue Viremia Titer, Antibody Response Pattern, and Virus Serotype Correlate with Disease Severity
David W. Vaughn,Sharone Green,Siripen Kalayanarooj,Bruce L. Innis,Suchitra Nimmannitya,Saroj Suntayakorn,Timothy P. Endy,Boonyos Raengsakulrach,Alan L. Rothman,Francis A. Ennis,Ananda Nisalak +10 more
TL;DR: Higher peak titers were associated with increased disease severity for the 31 patients with a peak titer identified, and increased dengue disease severity correlated with high viremia titer, secondary d Dengue virus infection, and DEN-2 virus type.
Journal ArticleDOI
Epidemic dengue/dengue hemorrhagic fever as a public health, social and economic problem in the 21st century
TL;DR: Dengue fever/dengue hemorrhagic fever is now one of the most important public health problems in tropical developing countries and also has major economic and societal consequences.
Journal ArticleDOI
Emerging flaviviruses: the spread and resurgence of Japanese encephalitis, West Nile and dengue viruses
TL;DR: Three examples of emerging and resurging diseases of global significance are described: the resurgence of dengue in tropical and subtropical areas of the world, and the spread and establishment of Japanese encephalitis and West Nile viruses in new habitats and environments.
References
More filters
Journal ArticleDOI
Confidence limits on phylogenies: an approach using the bootstrap.
TL;DR: The recently‐developed statistical method known as the “bootstrap” can be used to place confidence intervals on phylogenies and shows significant evidence for a group if it is defined by three or more characters.
Journal ArticleDOI
Dengue and Dengue Hemorrhagic Fever
TL;DR: A review of the changing epidemiology of dengue and hemorrhagic fever by geographic region, the natural history and transmission cycles, clinical diagnosis of both Dengue fever and DVF, serologic and virologic laboratory diagnoses, pathogenesis, surveillance, prevention, and control can be found in this paper.
Dengue and dengue hemorrhagic fever.
TL;DR: A major challenge for public health officials in all tropical areas of the world is to devleop and implement sustainable prevention and control programs that will reverse the trend of emergent dengue hemorrhagic fever.
Book
Emerging Infections: Microbial Threats to Health in the United States
TL;DR: Rich in information, this volume highlights risk factors for the emergence of microbial threats to health, warns against complacency in public health, and promotes early prevention as a cost-effective and crucial strategy for maintaining public health in the United States and worldwide.
Journal ArticleDOI
Dengue: the risk to developed and developing countries
TL;DR: At the root of the emergence of dengue as a major health problem are changes in human demography and behavior, leading to unchecked populations of and increased exposure to the principal domestic mosquito vector, Aedes aegypti.