Osteonecrosis of the Femoral Head: an Updated Review of ARCO on Pathogenesis, Staging and Treatment.
Jeremy T. Hines,Woo Lam Jo,Quanjun Cui,Michael A. Mont,Kyung-Hoi Koo,Edward Y. Cheng,Stuart B. Goodman,Yong-Chan Ha,Phillippe Hernigou,Lynne C. Jones,Shin Yoon Kim,Takashi Sakai,Nobuhiko Sugano,Takuaki Yamamoto,Mel S. Lee,Dewei Zhao,Wolf Drescher,Tae-Young Kim,Young-Kyun Lee,Byung-Ho Yoon,Seung-Hoon Baek,Wataru Ando,Hong Seok Kim,Jung Wee Park +23 more
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TLDR
In this paper, a review of the pathogenesis, classification criteria, staging system, and treatment of non-traumatic osteonecrosis of the femoral head (ONFH) is presented.Abstract:
Non-traumatic osteonecrosis of the femoral head (ONFH) usually affects adults younger than 50 years and frequently leads to femoral head collapse and subsequent arthritis of the hip. It is becoming more prevalent along with increasing use of corticosteroids for the adjuvant therapy of leukemia and other myelogenous diseases as well as management of organ transplantation. This review updated knowledge on the pathogenesis, classification criteria, staging system, and treatment of ONFH.read more
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The 2021 Association Research Circulation Osseous Classification for Early-Stage Osteonecrosis of the Femoral Head-CT Based Study.
Kyung-Hoi Koo,Michael A. Mont,Quanjun Cui,Jeremy T. Hines,Byung-Ho Yoon,Wendy M. Novicoff,Yunjong Lee,Edward Y. Cheng,Wolf Drescher,Philippe Hernigou,Shin-Yoon Kim,Nobuhiko Sugano,Dewei Zhao,Yong-Chan Ha,Stuart B. Goodman,Takashi Sakai,Lynne C. Jones,Mel S. Lee,Takuaki Yamamoto,Young-Kyun Lee,Yusuhn Kang,James Burgess,Dennis Q. Chen,Nicole D. Quinlan,Jianzhong Xu,Jung Wee Park,Hong-Seok Kim +26 more
TL;DR: In this paper , the authors developed a novel classification for early-stage osteonecrosis of the femoral head (ONFH), which is more reliable and valid when compared to previous 3 classifications: Steinberg, modified Kerboul, and Japanese Investigation Committee classifications.
Journal ArticleDOI
Decreased plasma CXCL12/SDF-1 concentrations may reflect disease severity of non-traumatic osteonecrosis of femoral head.
Shao-wei Zheng,Chun-han Sun,Zhilin Wen,Wei-le Liu,Xu Li,Tian-yu Chen,Yu-Cong Zou,Hao-bo Zhong,Zhanjun Shi +8 more
TL;DR: In this paper , the potential association of serum CXCL12 with disease severity in non-traumatic ONFH patients was investigated by measuring the enzyme-linked immunosorbent assay.
Journal ArticleDOI
Polymer Scaffolds-Enhanced Bone Regeneration in Osteonecrosis Therapy
Hengliang Dong,Tongtong Zhu,Mingran Zhang,Dapeng Wang,Xukai Wang,Guanning Huang,Shuaishuai Wang,Minglei Zhang +7 more
TL;DR: In this article, a review of applying polymers in osteonecrosis therapy is presented, and the development of biofunctionalized composite polymers based on the polymers combined with different bioactive substances is discussed.
Journal ArticleDOI
Steroid-induced osteonecrosis
TL;DR: In this article , the authors discuss the pathogenesis, risk factors, diagnosis, staging, and management of osteonecrosis associated with glucocorticoid treatment in general practice, rheumatology and clinical immunology, among others.
Journal ArticleDOI
Autologous Marrow Mesenchymal Stem Cell Driving Bone Regeneration in a Rabbit Model of Femoral Head Osteonecrosis
Ilenia Mastrolia,Andrea Giorgini,Alba Murgia,Pietro Loschi,Tiziana Petrachi,Valeria Rasini,Massimo Pinelli,Valentina Pinto,Francesca Lolli,Chiara Chiavelli,Giulia Grisendi,Maria Cristina Baschieri,Giorgio De Santis,Fabio Catani,Massimo Dominici,Elena Veronesi +15 more
TL;DR: The data support the use of ON+BM-MSCs as a promising autologous therapeutic tool to treat ON, paving the way for a more consolidated use into the clinical settings.
References
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