Outcome-centered antiepileptic therapy: Rate, rhythm and relief.: Implementing AAN Epilepsy Quality Measures in clinical practice.
TLDR
This article addresses the current conceptual framework that informs clinical evaluation of epilepsy, explores gaps between development of treatment options, quality measures and clinical goals, and proposes an outcome-centered approach that bridges these gaps with the aim of improving patient and population-level clinical outcomes in epilepsy.About:
This article is published in Epilepsy & Behavior.The article was published on 2015-12-01 and is currently open access. It has received 0 citations till now. The article focuses on the topics: Quality of life (healthcare) & Clinical trial.read more
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Journal ArticleDOI
Early Identification of Refractory Epilepsy
TL;DR: Patients who have many seizures before therapy or who have an inadequate response to initial treatment with antiepileptic drugs are likely to have refractory epilepsy.
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Definition of drug resistant epilepsy: consensus proposal by the ad hoc Task Force of the ILAE Commission on Therapeutic Strategies.
Patrick Kwan,Alexis Arzimanoglou,Anne T. Berg,Martin J. Brodie,W. Allen Hauser,Gary W. Mathern,Solomon L. Moshé,Emilio Perucca,Samuel Wiebe,Jacqueline A. French +9 more
TL;DR: It is proposed as a testable hypothesis that drug resistant epilepsy is defined as failure of adequate trials of two tolerated, appropriately chosen and used antiepileptic drug schedules to achieve sustained seizure freedom.
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Definition of drug resistant epilepsy: Consensus proposal by the ad hoc Task Force of the ILAE Commission on Therapeutic Strategies
TL;DR: This research presents a novel and scalable approach called “informed consent” that aims to provide real-time information about the pros and cons of surgery on the basis of prior history and once-in-a-lifetime data.
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Patterns of treatment response in newly diagnosed epilepsy
TL;DR: Most patients with newly diagnosed epilepsy had a constant course which could usually be predicted early and the chance of seizure freedom declined with successive drug regimens, most markedly from the first to the third and among patients with localization-related epilepsies.
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Resective Epilepsy Surgery for Drug-Resistant Focal Epilepsy: A Review
TL;DR: Epilepsy surgery was less effective when there were extratemporal lesions, the epilepsy was not associated with a structural lesion, or both, and quality of life improved after surgery but improved the most in patients who were seizure-free after surgery.