Journal ArticleDOI
Palladium catalyzed ligand-free Suzuki cross-coupling reaction
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In this article, a ligand-free Suzuki cross-coupling reaction between aryl halides and boronic acids using palladium chloride as catalyst in toluene has been developed.About:
This article is published in Catalysis Communications.The article was published on 2008-03-15. It has received 50 citations till now. The article focuses on the topics: Suzuki reaction & Heck reaction.read more
Citations
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Oxygen-promoted PdCl2-catalyzed ligand-free Suzuki reaction in aqueous media
TL;DR: Results show that an aerobic atmosphere demonstrates a positive effect on the reactivity of the Suzuki reaction in an aqueous media and a negative effect in a pure organic solvent, which exhibits that the water plays a crucial role for the function of the atmosphere on the palladium-catalyzed ligand-free Suzuki reaction.
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Palladium catalyzed C–C and C–N bond forming reactions: an update on the synthesis of pharmaceuticals from 2015–2020
TL;DR: In this article, the authors describe pharmaceuticals approved by the United States Food and Drug Administration (the U.S. FDA) between 2015 and 2020, which were synthesized via Pd-catalyzed cross-coupling reactions for the construction of carbon-carbon (C)-C and carbon-nitrogen (C-N) bonds.
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A fast and oxygen-promoted protocol for the ligand-free Suzuki reaction of 2-halogenated pyridines in aqueous media
Chun Liu,Weibo Yang +1 more
TL;DR: A fast protocol has been developed for the construction of 2-aryl-substituted pyridine derivatives by the oxygen-promoted, ligand-free, Pd(OAc)2-catalyzed Suzuki reaction of 2 -halogenated pyridines in aqueous isopropanol.
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Palladium-scavenging self-assembled hybrid hydrogels – reusable highly-active green catalysts for Suzuki–Miyaura cross-coupling reactions
TL;DR: From waste to wealth – a self-assembled hydrogel remediates palladium from solution down to sub-ppm levels, and the resulting gel, which has embedded Pd nanoparticles, acts as a green and efficient catalyst for Suzuki–Miyaura cross-coupling reactions.
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In situ generation of palladium nanoparticles: ligand-free palladium catalyzed ultrafast Suzuki–Miyaura cross-coupling reaction in aqueous phase at room temperature
TL;DR: In this paper, an ultrafast and highly efficient ligand-free Suzuki-Miyaura cross-coupling reaction between aryl bromides/iodides and aryboronic acids using palladium chloride as catalyst in PEG400/H 2 O in air at room temperature has been developed.
References
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Palladium-catalyzed cross-coupling reactions of organoboron compounds
Norio Miyaura,Akira Suzuki +1 more
TL;DR: In this paper, a cross-coupling reaction is proposed for coupling 1 -Alkenylboron Derivatives: Synthesis of Conjugated Dienes 6.
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Recent advances in the cross-coupling reactions of organoboron derivatives with organic electrophiles, 1995–1998
TL;DR: The palladium-catalyzed cross-coupling reaction between organoboron compounds and organic halides or triflates provides a powerful and general methodology for the formation of carbon-carbon bonds as discussed by the authors.
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Palladium-Catalyzed Coupling Reactions of Aryl Chlorides
Adam F. Littke,Gregory C. Fu +1 more
TL;DR: This review summarizes both the seminal early work and the exciting recent developments in the area of palladium-catalyzed couplings of aryl chlorides.
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Catalysts for Suzuki−Miyaura Coupling Processes: Scope and Studies of the Effect of Ligand Structure
TL;DR: Structural studies of various 1.Pd complexes are presented along with computational data that help elucidate the efficacy that 1 imparts on Suzuki-Miyaura coupling processes, and a comparison of the reactions is presented that is informative in determining the relative importance of ligand bulk and electron-donating ability in the high activity of catalysts derived from ligands of this type.
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Palladium-catalyzed Suzuki-Miyaura cross-coupling reactions of potassium aryl- and heteroaryltrifluoroborates
Gary A. Molander,Betina Biolatto +1 more
TL;DR: An extended study of the reactivity of potassium aryl- and heteroaryltrifluoroborates in Suzuki-Miyaura cross-coupling reactions is presented, finding a low loading of PdCl(2)(dppf).
Related Papers (5)
Palladium-catalyzed cross-coupling reactions of organoboron compounds
Norio Miyaura,Akira Suzuki +1 more