Q1. What are the contributions in "Pathogenesis and pathophysiology of endometriosis" ?
This work reviews the disease process from theories regarding origin to the molecular basis for disease sequelae.
Pathogenesis and pathophysiology of endometriosis
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The disease process is reviewed from theories regarding origin to the molecular basis for disease sequelae and a thorough understanding of the histopathogenesis and pathophysiology of endometriosis is essential to the development of novel diagnostic and treatment approaches for this debilitating condition.About:
This article is published in Fertility and Sterility.The article was published on 2012-09-01 and is currently open access. It has received 1066 citations till now. The article focuses on the topics: Endometriosis & Pelvic pain.read more
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Endometriosis: pathogenesis and treatment
TL;DR: Endometriosis is estrogen-dependent, manifests during reproductive years and is associated with pain and infertility, while lesion eradication is considered a fertility-enhancing procedure, the benefit on reproductive performance is moderate.
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What we know about primary dysmenorrhea today: a critical review
TL;DR: The extensive multi-factorial impact of dysmenorrhea is demonstrated, evident even in phases of the menstrual cycle when women are not experiencing menstrual pain, illustrating that long-term differences in pain perception extend outside of the painful menstruation phase.
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Theories on the Pathogenesis of Endometriosis
TL;DR: This review examines existing theories on the initiation and propagation of different types of endometriotic lesions, as well as critically appraises the myriad of biologically relevant evidence that support or oppose each of the proposed theories.
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Pathophysiology and Immune Dysfunction in Endometriosis.
Soo Hyun Ahn,Stephany P. Monsanto,Caragh Miller,Sukhbir S. Singh,Richard Thomas,Chandrakant Tayade +5 more
TL;DR: The role of hormones, immune cells, and cytokine signaling is highlighted, in addition to discussing the current pharmaceutical options available for management of pain symptoms in women with endometriosis.
References
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Peritoneal endometriosis due to the menstrual dissemination of endometrial tissue into the peritoneal cavity
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Epidemiology of endometriosis
Brenda Eskenazi,Marcella Warner +1 more
TL;DR: Age is the only sociodemographic characteristic for which a consistent positive relationship has been observed and the risk of endometriosis appears to increase for reproductive health factors that may relate to increased exposure to menstruation and decrease for personal habits.
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Impact of endometriosis on quality of life and work productivity: a multicenter study across ten countries
Kelechi E Nnoaham,Lone Hummelshoj,Premila Webster,Thomas D'Hooghe,Fiorenzo De Cicco Nardone,Carlo de Cicco Nardone,Crispin Jenkinson,Stephen Kennedy,Krina T. Zondervan,Krina T. Zondervan +9 more
TL;DR: Endometriosis impairs HRQoL and work productivity across countries and ethnicities, yet women continue to experience diagnostic delays in primary care, and a higher index of suspicion is needed to expedite specialist assessment of symptomatic women.
Journal Article
Retrograde menstruation in healthy women and in patients with endometriosis.
TL;DR: The present observations indicate that retrograde menstruation through the fallopian tubes into the peritoneal cavity is a very common physiologic event in all menstruating women with patent tubes.