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Journal ArticleDOI

Patients with type 2 diabetes show a greater decline in muscle mass, muscle strength, and functional capacity with aging.

TLDR
Exercise intervention programs should be individualized to specifically target muscle mass, strength, and functional capacity in the older population with type 2 diabetes.
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This article is published in Journal of the American Medical Directors Association.The article was published on 2013-08-01. It has received 350 citations till now. The article focuses on the topics: Sarcopenia & Skeletal muscle.

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Citations
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Journal ArticleDOI

Prevalence, incidence, and clinical impact of sarcopenia: facts, numbers, and epidemiology—update 2014

TL;DR: The definition of sarcopenia is now defined as a decline in walking speed or grip strength associated with low muscle mass, which leads to loss of mobility and function, falls, and mortality.
Journal ArticleDOI

Benefits for Type 2 Diabetes of Interrupting Prolonged Sitting With Brief Bouts of Light Walking or Simple Resistance Activities

TL;DR: Interrupting prolonged sitting with brief bouts of light-intensity walking or simple resistance activities or SRA attenuates acute postprandial glucose, insulin, C-peptide, and triglyceride responses in adults with T2D.
Book ChapterDOI

Sex Differences in Body Composition.

TL;DR: Sex differences of regional adipose tissue, muscle mass, ectopic lipids, and brown adipose tissues and their effects on cardiometabolic risk will be discussed and novel imaging techniques to quantify these body composition compartments noninvasively will be described.
Journal ArticleDOI

Frailty, Sarcopenia and Diabetes

TL;DR: The relationship of frailty and sarcopenia to diabetes mellitus is explored and it is shown that persons with diabetes are at increased risk of mobility disability and disability in instrumental activities of daily living and activities ofdaily living.
References
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Journal ArticleDOI

Biochemistry and molecular cell biology of diabetic complications

TL;DR: This integrating paradigm provides a new conceptual framework for future research and drug discovery in diabetes-specific microvascular disease and seems to reflect a single hyperglycaemia-induced process of overproduction of superoxide by the mitochondrial electron-transport chain.
Journal ArticleDOI

Compendium of physical activities: an update of activity codes and MET intensities.

TL;DR: An updated version of the Compendium of Physical Activities, a coding scheme that classifies specific physical activity (PA) by rate of energy expenditure, is provided to enhance the comparability of results across studies using self-reports of PA.
Journal ArticleDOI

A short physical performance battery assessing lower extremity function: association with self-reported disability and prediction of mortality and nursing home admission.

TL;DR: Evidence is presented that performance measures can validly characterize older persons across a broad spectrum of lower extremity function and that performance and self-report measures may complement each other in providing useful information about functional status.
Journal ArticleDOI

Advanced glycation end products: sparking the development of diabetic vascular injury.

TL;DR: Because of the emerging evidence about the adverse effects of AGEs on the vasculature of patients with diabetes, a number of different therapies to inhibit A GEs are under investigation.
Journal ArticleDOI

Midlife hand grip strength as a predictor of old age disability.

TL;DR: Among healthy 45- to 68-year-old men, hand grip strength was highly predictive of functional limitations and disability 25 years later, suggesting good muscle strength in midlife may protect people from old age disability by providing a greater safety margin above the threshold of disability.
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Type 2 diabetes, muscle strength, and impaired physical function: the tip of the iceberg?

Patients with type 2 diabetes show a greater decline in muscle mass, muscle strength, and functional capacity with aging.