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Bronwyn A. Kingwell
Researcher at Baker IDI Heart and Diabetes Institute
Publications - 311
Citations - 20152
Bronwyn A. Kingwell is an academic researcher from Baker IDI Heart and Diabetes Institute. The author has contributed to research in topics: Blood pressure & Arterial stiffness. The author has an hindex of 74, co-authored 296 publications receiving 18123 citations. Previous affiliations of Bronwyn A. Kingwell include University of Michigan & University of Cambridge.
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Journal ArticleDOI
Breaking Up Prolonged Sitting Reduces Postprandial Glucose and Insulin Responses
David W. Dunstan,Bronwyn A. Kingwell,Robyn N. Larsen,Genevive N Healy,Genevive N Healy,Ester Cerin,Marc T. Hamilton,Jonathan E. Shaw,Jonathan E. Shaw,David A. Bertovic,Paul Zimmet,Paul Zimmet,Jo Salmon,Neville Owen,Neville Owen +14 more
TL;DR: Interrupting sitting time with short bouts of light- or moderate-intensity walking lowers postprandial glucose and insulin levels in overweight/obese adults and may improve glucose metabolism and potentially be an important public health and clinical intervention strategy for reducing cardiovascular risk.
Journal ArticleDOI
Pulse pressure—a review of mechanisms and clinical relevance
TL;DR: The origin, clinical relevance and treatment of pulse pressure is reviewed, and a distributed compliance model of the arterial circulation provides a framework for understanding the causes, effects and potential treatment of elevations in PP.
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HSP72 protects against obesity-induced insulin resistance.
Jason Chung,Anh-Khoi Nguyen,Darren C. Henstridge,Anna G Holmes,Stanley M H Chan,Jose L Mesa,Grame I I Lancaster,Robert J Southgate,Clinton R. Bruce,Stephen J. Duffy,Ibolya Horváth,Ruben Mestril,Matthew J. Watt,Philp L Hooper,Bronwyn A. Kingwell,László Vígh,Andrea L. Hevener,Andrea L. Hevener,Mark A. Febbraio +18 more
TL;DR: An essential role is identified for HSP72 in blocking inflammation and preventing insulin resistance in the context of genetic obesity or high-fat feeding and protection against diet- or obesity-induced hyperglycemia, hyperinsulinemia, glucose intolerance, and insulin resistance.
Journal ArticleDOI
Heart rate spectral analysis, cardiac norepinephrine spillover, and muscle sympathetic nerve activity during human sympathetic nervous activation and failure.
Bronwyn A. Kingwell,Jane M. Thompson,David M. Kaye,Grant A. McPherson,Garry L. Jennings,Murray D. Esler +5 more
TL;DR: HRV at 0.1 Hz depends on factors in addition to cardiac sympathetic nerve firing rates, including multiple neural reflexes, cardiac adrenergic receptor sensitivity, postsynaptic signal transduction, and electrochemical coupling, and is not directly related to cardiac norepinephrine spillover, which is a more direct measure of the sympathetic nerve fired rate.
Journal ArticleDOI
High-Density Lipoprotein Modulates Glucose Metabolism in Patients With Type 2 Diabetes Mellitus
Brian G. Drew,Stephen J. Duffy,Melissa F. Formosa,Alaina K. Natoli,Darren C. Henstridge,Darren C. Henstridge,Sally A. Penfold,Walter G. Thomas,Nigora Mukhamedova,Barbora de Courten,Josephine M. Forbes,Felicia Y. T. Yap,David M. Kaye,Gerrit van Hall,Mark A. Febbraio,Bruce E. Kemp,Dmitri Sviridov,Gregory R. Steinberg,Bronwyn A. Kingwell +18 more
TL;DR: In this paper, a double-blind, placebo-controlled crossover study was conducted on 13 patients with type 2 diabetes mellitus who received both intravenous reconstituted HDL (rHDL: 80 mg/kg over 4 hours) and placebo on separate days in a double blind, placebo controlled crossover study.