Journal ArticleDOI
Pediatric Hospitalizations Associated with 2009 Pandemic Influenza A (H1N1) in Argentina
Romina Libster,Jimena Bugna,Silvina Coviello,Diego R. Hijano,Mariana Dunaiewsky,Natalia Reynoso,María L Cavalieri,Maria C. Guglielmo,M. Soledad Areso,Tomas Gilligan,Fernanda Santucho,Graciela Cabral,Gabriela Gregorio,Rina Moreno,Maria I. Lutz,Alicia L. Panigasi,Liliana Saligari,Mauricio T. Caballero,Rodrigo M. Egües Almeida,Maria Emilia Gutierrez Meyer,Maria D. Neder,María C Davenport,María de la Paz Del Valle,Valeria S. Santidrian,Guillermina Mosca,Mercedes Garcia Domínguez,Liliana Alvarez,Patricia Landa,Ana Pota,Norma Boloñati,Ricardo S. Dalamón,Victoria I. Sanchez Mercol,Marco A. Espinoza,Juan Carlos Peuchot,Ariel Karolinski,Miriam Bruno,Ana Borsa,Fernando Ferrero,Angel Bonina,Margarita Ramonet,Lidia C. Albano,Nora Luedicke,Elias Alterman,Vilma Savy,Elsa Baumeister,James D. Chappell,Kathryn M. Edwards,Guillermina A. Melendi,Fernando P. Polack +48 more
Reads0
Chats0
TLDR
Pandemic 2009 H1N1 influenza was associated with pediatric death rates that were 10 times the rates for seasonal influenza in previous years.Abstract:
BACKGROUND While the Northern Hemisphere experiences the effects of the 2009 pandemic influenza A (H1N1) virus, data from the recent influenza season in the Southern Hemisphere can provide important information on the burden of disease in children. METHODS We conducted a retrospective case series involving children with acute infection of the lower respiratory tract or fever in whom 2009 H1N1 influenza was diagnosed on reverse-transcriptase polymerase-chain-reaction assay and who were admitted to one of six pediatric hospitals serving a catchment area of 1.2 million children. We compared rates of admission and death with those among age-matched children who had been infected with seasonal influenza strains in previous years. RESULTS Between May and July 2009, a total of 251 children were hospitalized with 2009 H1N1 influenza. Rates of hospitalization were double those for seasonal influenza in 2008. Of the children who were hospitalized, 47 (19%) were admitted to an intensive care unit, 42 (17%) required mechanical ventilation, and 13 (5%) died. The overall rate of death was 1.1 per 100,000 children, as compared with 0.1 per 100,000 children for seasonal influenza in 2007. (No pediatric deaths associated with seasonal influenza were reported in 2008.) Most deaths were caused by refractory hypoxemia in infants under 1 year of age (death rate, 7.6 per 100,000). CONCLUSIONS Pandemic 2009 H1N1 influenza was associated with pediatric death rates that were 10 times the rates for seasonal influenza in previous years.read more
Citations
More filters
Journal ArticleDOI
Clinical aspects of pandemic 2009 influenza A (H1N1) virus infection.
Bautista E,Tawee Chotpitayasunondh,Zhancheng Gao,Scott A. Harper,Michael W. Shaw,Timothy M. Uyeki,Zaki,Frederick G. Hayden,David S.C. Hui,Joel Kettner,Anand Kumar,Lim M,Nikki Shindo,Charles R. Penn,Nicholson Kg +14 more
TL;DR: A review of virologic, epidemiologic, and clinical data on 2009 H1N1 virus infections and summarizes key issues for clinicians worldwide can be found in this paper, where a novel influenza A virus of swine origin caused human infection and acute respiratory illness in Mexico.
Antiviral agents for the treatment and chemoprophylaxis of influenza --- recommendations of the Advisory Committee on Immunization Practices (ACIP).
Anthony E. Fiore,Alicia M. Fry,David K. Shay,Larisa V. Gubareva,Joseph S. Bresee,Timothy M. Uyeki +5 more
TL;DR: This report updates previous recommendations by CDC's Advisory Committee on Immunization Practices (ACIP) regarding the use of antiviral agents for the prevention and treatment of influenza and provides a summary of the effectiveness and safety of antivirus treatment medications.
Journal ArticleDOI
Populations at risk for severe or complicated influenza illness: systematic review and meta-analysis
Dominik Mertz,Tae Hyong Kim,Jennie Johnstone,Po-Po Lam,Po-Po Lam,Stefan P. Kuster,Shaza A. Fadel,Dat Tran,Eduardo Fernandez,Neera Bhatnagar,Mark Loeb +10 more
TL;DR: The level of evidence to support risk factors for influenza related complications is low and some well accepted risk factors, including pregnancy and ethnicity, could not be confirmed as risks.
Journal ArticleDOI
The 2009 A (H1N1) influenza virus pandemic: A review.
TL;DR: The need for an increased surveillance of influenza virus circulation in swine is outlined, and all currently registered vaccines were found to be safe and to elicit potentially protective antibody responses after the administration of a single dose of vaccine.
Journal ArticleDOI
Effects of influenza on pregnant women and infants.
TL;DR: The risks for influenza-associated complications among pregnant women and infants <6 months old are reviewed and influenza vaccination during pregnancy is shown to decrease the risk of influenza and its complications.
References
More filters
Journal ArticleDOI
Mortality Associated With Influenza and Respiratory Syncytial Virus in the United States
William W. Thompson,David K. Shay,Eric Weintraub,Lynnette Brammer,Nancy Cox,Larry J. Anderson,Keiji Fukuda +6 more
TL;DR: Mortality associated with both influenza and RSV circulation disproportionately affects elderly persons, and influenza deaths have increased substantially in the last 2 decades, in part because of aging of the population, highlighting the need for better prevention measures, including more effective vaccines and vaccination programs for elderly persons.
Journal ArticleDOI
Hospitalized patients with 2009 H1N1 influenza in the United States, April-June 2009.
Seema Jain,Laurie Kamimoto,Anna M. Bramley,Ann Schmitz,Stephen R. Benoit,Janice K. Louie,David E. Sugerman,Jean K Druckenmiller,Kathleen A. Ritger,Rashmi Chugh,Supriya Jasuja,Meredith Deutscher,Sanny Chen,John D Walker,Jeffrey S. Duchin,Susan M. Lett,Susan Soliva,Eden V. Wells,David L. Swerdlow,David L. Swerdlow,Timothy M. Uyeki,Anthony E. Fiore,Sonja J. Olsen,Alicia M. Fry,Carolyn B. Bridges,Lyn Finelli +25 more
TL;DR: Data suggest that the use of antiviral drugs was beneficial in hospitalized patients, especially when such therapy was initiated early, and patients seemed to benefit from antiviral therapy.
Journal ArticleDOI
Pneumonia and Respiratory Failure from Swine-Origin Influenza A (H1N1) in Mexico
Rogelio Pérez-Padilla,Daniela de la Rosa-Zamboni,Samuel Ponce de Leon,Mauricio Hernandez,Francisco Quiñones-Falconi,Edgar Bautista,Alejandra Ramírez-Venegas,Jorge Rojas-Serrano,Christopher E. Ormsby,Ariel Corrales,Anjarath Higuera,Edgar Mondragon,Jose Angel Cordova-Villalobos +12 more
TL;DR: The clinical and epidemiologic characteristics of persons hospitalized for pneumonia at the national tertiary hospital for respiratory illnesses in Mexico City who had laboratory-confirmed S-OIV infection, also known as swine flu are described.
Journal ArticleDOI
Cross-Reactive Antibody Responses to the 2009 Pandemic H1N1 Influenza Virus
Kathy Hancock,Vic Veguilla,Xiuhua Lu,Weimin Zhong,Eboneé N. Butler,Hong Sun,Feng Liu,Libo Dong,Joshua DeVos,Paul Gargiullo,T . Lynnette. Brammer,Nancy J. Cox,Terrence M. Tumpey,Jacqueline M. Katz +13 more
TL;DR: Vaccination with recent seasonal nonadjuvanted or adjuvanted influenza vaccines induced little or no cross-reactive antibody response to 2009 H1N1 in any age group.
Journal ArticleDOI
H1N1 2009 influenza virus infection during pregnancy in the USA
Denise J. Jamieson,Margaret A. Honein,Sonja A. Rasmussen,Jennifer Williams,David L. Swerdlow,Matthew Biggerstaff,Stephen Lindstrom,Janice K. Louie,Cara M. Christ,Susan Bohm,Vincent P. Fonseca,Kathleen A. Ritger,Daniel J Kuhles,Paula Eggers,Hollianne Bruce,Heidi A Davidson,Emily Lutterloh,Meghan L. Harris,Colleen Burke,Noelle M. Cocoros,Lyn Finelli,Kitty MacFarlane,Bo Shu,Sonja J Olsen +23 more
TL;DR: Cases and deaths associated with pandemic H1N1 virus in pregnant women identified in the USA during the first month of the present outbreak lend support to the present recommendation to promptly treat pregnant women with H 1N1 influenza virus infection with anti-influenza drugs.
Related Papers (5)
Hospitalized patients with 2009 H1N1 influenza in the United States, April-June 2009.
Seema Jain,Laurie Kamimoto,Anna M. Bramley,Ann Schmitz,Stephen R. Benoit,Janice K. Louie,David E. Sugerman,Jean K Druckenmiller,Kathleen A. Ritger,Rashmi Chugh,Supriya Jasuja,Meredith Deutscher,Sanny Chen,John D Walker,Jeffrey S. Duchin,Susan M. Lett,Susan Soliva,Eden V. Wells,David L. Swerdlow,David L. Swerdlow,Timothy M. Uyeki,Anthony E. Fiore,Sonja J. Olsen,Alicia M. Fry,Carolyn B. Bridges,Lyn Finelli +25 more
Pneumonia and Respiratory Failure from Swine-Origin Influenza A (H1N1) in Mexico
Critically ill patients with 2009 influenza A(H1N1) infection in Canada.
Anand Kumar,Ryan Zarychanski,Ruxandra Pinto,Deborah J. Cook,John C. Marshall,Jacques Lacroix,Tom Stelfox,Sean M. Bagshaw,Karen Choong,Francois Lamontagne,Alexis F. Turgeon,Stephen E. Lapinsky,Stéphane P. Ahern,Orla Smith,Faisal Siddiqui,Philippe Jouvet,Kosar Khwaja,Lauralyn McIntyre,Kusum Menon,Jamie Hutchison,David Hornstein,Ari R. Joffe,François Lauzier,Jeffrey M. Singh,Tim Karachi,Kim Wiebe,Kendiss Olafson,Clare D. Ramsey,Sat Sharma,Peter Dodek,Maureen O. Meade,Richard I. Hall,Robert A. Fowler +32 more