T
Tim Karachi
Researcher at McMaster University
Publications - 41
Citations - 2184
Tim Karachi is an academic researcher from McMaster University. The author has contributed to research in topics: Intensive care unit & Randomized controlled trial. The author has an hindex of 12, co-authored 31 publications receiving 1869 citations. Previous affiliations of Tim Karachi include St. Joseph's Healthcare Hamilton & Lawson Health Research Institute.
Papers
More filters
Journal ArticleDOI
Critically ill patients with 2009 influenza A(H1N1) infection in Canada.
Anand Kumar,Ryan Zarychanski,Ruxandra Pinto,Deborah J. Cook,John C. Marshall,Jacques Lacroix,Tom Stelfox,Sean M. Bagshaw,Karen Choong,Francois Lamontagne,Alexis F. Turgeon,Stephen E. Lapinsky,Stéphane P. Ahern,Orla Smith,Faisal Siddiqui,Philippe Jouvet,Kosar Khwaja,Lauralyn McIntyre,Kusum Menon,Jamie Hutchison,David Hornstein,Ari R. Joffe,François Lauzier,Jeffrey M. Singh,Tim Karachi,Kim Wiebe,Kendiss Olafson,Clare D. Ramsey,Sat Sharma,Peter Dodek,Maureen O. Meade,Richard I. Hall,Robert A. Fowler +32 more
TL;DR: Critical illness due to 2009 influenza A(H1N1) in Canada occurred rapidly after hospital admission, often in young adults, and was associated with severe hypoxemia, multisystem organ failure, a requirement for prolonged mechanical ventilation, and the frequent use of rescue therapies.
Journal ArticleDOI
Venous thromboembolism and bleeding in critically ill patients with severe renal insufficiency receiving dalteparin thromboprophylaxis: prevalence, incidence and risk factors
Deborah J. Cook,James D. Douketis,Maureen O. Meade,Gordon H. Guyatt,Nicole Zytaruk,John Granton,Yoanna Skrobik,Martin Albert,Robert A. Fowler,Paul C. Hébert,G. Pagliarello,Jan O. Friedrich,Andreas Freitag,Tim Karachi,Christian Rabbat,Diane Heels-Ansdell,William Geerts,Mark Crowther +17 more
TL;DR: In ICU patients with renal insufficiency, the incidence of DVT and major bleeding are considerable but appear related to patient comorbidities rather than to an inadequate or excessive anticoagulant from thromboprophylaxis with dalteparin.
Journal ArticleDOI
Withholding Pantoprazole for Stress Ulcer Prophylaxis in Critically Ill Patients: A Pilot Randomized Clinical Trial and Meta-Analysis.
Waleed Alhazzani,Gordon H. Guyatt,Mohammed Alshahrani,Adam M. Deane,John C. Marshall,Richard I. Hall,John Muscedere,Shane W. English,Shane W. English,François Lauzier,Lehana Thabane,Lehana Thabane,Yaseen M. Arabi,Tim Karachi,Bram Rochwerg,Simon Finfer,Nick Daneman,Fayez Alshamsi,Nicole Zytaruk,Diane Heel-Ansdell,Deborah J. Cook +20 more
TL;DR: The Reevaluating the Inhibition of Stress Erosions Pilot Trial determined the feasibility of undertaking a larger trial investigating the efficacy and safety of withholding proton pump inhibitors in critically ill patients and found there was no alarming increase in the risk of upper gastrointestinal bleeding.
Journal ArticleDOI
Effect of Probiotics on Incident Ventilator-Associated Pneumonia in Critically Ill Patients: A Randomized Clinical Trial.
Jennie Johnstone,Maureen O. Meade,François Lauzier,John Marshall,Erick Duan,Joanna C. Dionne,Yaseen M. Arabi,Diane Heels-Ansdell,Lehana Thabane,Daphnée Lamarche,Michael G. Surette,Nicole Zytaruk,Sangeeta Mehta,Peter Dodek,Lauralyn McIntyre,Shane W. English,Bram Rochwerg,Tim Karachi,William R. Henderson,Gordon Wood,Daniel Ovakim,Margaret S. Herridge,John Granton,M. Elizabeth Wilcox,Alberto Goffi,Henry T. Stelfox,Daniel J. Niven,John Muscedere,Francois Lamontagne,Frédérick D’Aragon,Charles St-Arnaud,Ian M Ball,Dave Nagpal,Martin Girard,Pierre Aslanian,Emmanuel Charbonney,David Williamson,Wendy I. Sligl,Jan O. Friedrich,Neill K. J. Adhikari,François Marquis,Patrick Archambault,Kosar Khwaja,Arnold S. Kristof,James Kutsogiannis,Ryan Zarychanski,Bojan Paunovic,Brenda Reeve,François Lellouche,Paul Hosek,Jennifer L Y Tsang,Alexandra Binnie,Sébastien Trop,Osama Loubani,Richard I. Hall,Robert Cirone,Steve Reynolds,Paul J Lysecki,Eyal Golan,Rodrigo Cartin-Ceba,Robert W. Taylor,Deborah J. Cook,Endotracheal Colonization Trial (Prospect) Investigators +62 more
TL;DR: In this paper, the authors evaluated the effect of L rhamnosus GG on preventing VAP, additional infections, and other clinically important outcomes in the intensive care unit (ICU).
Journal ArticleDOI
Risk factors and impact of major bleeding in critically ill patients receiving heparin thromboprophylaxis
François Lauzier,Donald M. Arnold,Donald M. Arnold,Christian Rabbat,Diane Heels-Ansdell,Ryan Zarychanski,Peter Dodek,Betty Jean Ashley,Martin Albert,Kosar Khwaja,Marlies Ostermann,Yoanna Skrobik,Robert A. Fowler,Lauralyn McIntyre,Joseph L. Nates,Tim Karachi,Renato D. Lopes,Nicole Zytaruk,Simon Finfer,Mark Crowther,Deborah J. Cook +20 more
TL;DR: As major bleeding has modifiable risk factors and is associated with in-hospital mortality, strategies to mitigate these factors should be evaluated in critically ill patients.