Performance of CT in the Preoperative Diagnosis of Cervical Lymph Node Metastasis in Patients with Papillary Thyroid Cancer: A Systematic Review and Meta-Analysis
TLDR
CT may be used as a complementary diagnostic method in addition to ultrasound for diagnosing cervical lymph node metastasis in patients with papillary thyroid cancer, though CT and ultrasound combined are superior to ultrasound only.Abstract:
BACKGROUND AND PURPOSE: Ultrasound has become widely accepted as the first imaging technique used for the assessment of cervical lymph node metastasis in patients with papillary thyroid cancer In this systematic review and meta-analysis, we evaluate the performance of CT for the preoperative diagnosis of cervical lymph node metastasis in patients with papillary thyroid cancer compared with ultrasound MATERIALS AND METHODS: Ovid-MEDLINE and EMBASE data bases were searched for studies regarding the use of CT to diagnose cervical lymph node metastasis The diagnostic performance of CT, ultrasound, and combined CT/ultrasound was assessed by using level-by-level and patient-based analyses We also performed meta-analyses on the basis of the central and lateral neck levels RESULTS: Nine eligible studies, including a total sample size of 1691 patients, were included CT showed a summary sensitivity of 62% (95% CI, 52%–70%) and specificity of 87% (95% CI, 80%–92%) for diagnosing cervical lymph node metastasis when using level-by-level analysis There was a positive correlation between the sensitivity and the false-positive rate (correlation coefficient, 0807) because of the threshold effect The summary sensitivity of combined CT/ultrasound (69%; 95% CI, 61%–77%) was significantly higher than ultrasound (51%; 95% CI, 42%–60%), though the summary specificity did not differ CONCLUSIONS: The diagnostic performances of CT and ultrasound are similar, though CT and ultrasound combined are superior to ultrasound only CT may be used as a complementary diagnostic method in addition to ultrasound for diagnosing cervical lymph node metastasis in patients with papillary thyroid cancerread more
Citations
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Journal ArticleDOI
Meta-analysis of ultrasound for cervical lymph nodes in papillary thyroid cancer: Diagnosis of central and lateral compartment nodal metastases.
Hengqiang Zhao,Hehe Li +1 more
TL;DR: Preoperative ultrasound demonstrates poor sensitivity in the diagnosis of central CLNM, and good diagnostic efficacy for lateral CLNM of PTC.
Journal ArticleDOI
Application of deep learning to the diagnosis of cervical lymph node metastasis from thyroid cancer with CT
TL;DR: A deep learning–based CAD system could accurately classify cervical LNM in patients with thyroid cancer on preoperative CT with an AUROC of 0.953, and based on its high accuracy, it is considered that this model may be useful in a clinical setting to detect LNM on preoperatively CT in patientsWith thyroid cancer.
Journal ArticleDOI
US-Guided Radiofrequency Ablation for Low-Risk Papillary Thyroid Microcarcinoma: Efficacy and Safety in a Large Population.
Hyun Kyung Lim,Se Jin Cho,Jung Hwan Baek,Kang Dae Lee,Chang Woo Son,Jung Min Son,Seon Mi Baek +6 more
TL;DR: The results suggest that RFA is an effective and safe option for treating low-risk PTMC patients who are of high surgical risk or refuse surgery.
Journal ArticleDOI
2021 Korean Thyroid Imaging Reporting and Data System and Imaging-Based Management of Thyroid Nodules: Korean Society of Thyroid Radiology Consensus Statement and Recommendations
Eun Ju Ha,Sae Rom Chung,Dong Gyu Na,Hye Shin Ahn,Jin Chung,Ji Ye Lee,Jeong Seon Park,Roh-Eul Yoo,Jung Hwan Baek,Sun Mi Baek,Seong Whi Cho,Yoon Jung Choi,Soo Yeon Hahn,So Lyung Jung,Ji Hoon Kim,Seul Kee Kim,Soo Jin Kim,Chang Yoon Lee,Ho Kyu Lee,Jeong Hyun Lee,Young Hen Lee,Hyun Kyung Lim,Jung Hee Shin,Jung Suk Sim,Jin Young Sung,Jung Hyun Yoon,Miyoung Choi +26 more
TL;DR: The Korean Society of Thyroid Radiology (KSThR) published consensus recommendations for US-based management of thyroid nodules in 2011 and revised them in 2016 as mentioned in this paper, which has contributed to the rapidly rising incidence of low risk papillary thyroid carcinoma over the last 20 years.
Journal ArticleDOI
Contemporary debates in adult papillary thyroid cancer management
TL;DR: This review discusses controversial issues in adult papillary thyroid cancer management at both ends of the disease spectrum and provides additional evidence that will decrease morbidity in low-risk patients and improve outcomes in those with distant metastatic disease.
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