Journal ArticleDOI
Photocontact dermatitis to cobalt salts.
TLDR
4 patients with chronic photocontact dermatitis were sensitive to cobalt salts and photo‐oxidation tests proved that photosensitizing was responsible for the patients' chronic actinic dermatitis.Abstract:
4 patients with chronic photocontact dermatitis were sensitive to cobalt salts. They presented as cases of contact dermatitis from cement or pig fodder with persistent lesions on exposed areas. Only 2 of them had standard patch test positive reactions to chromate and cobalt, but all showed positive photo-patch tests to cobalt. Photo-oxidation tests proved that are photosensitizing. Exposure to cobalt salts was responsible for the patients' chronic actinic dermatitis.read more
Citations
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Toxicological profile for cobalt
Obaid Faroon,Sam Keith +1 more
TL;DR: This edition supersedes any previously released draft or final profile and reflects a comprehensive and extensive evaluation, summary, and interpretation of available toxicologic and epidemiologic information on a substance.
Journal ArticleDOI
Metals and the skin.
TL;DR: It is clear that many diverse factors determine the ability of metal-based species to permeate biological membranes, not all of which have been fully defined and considerably more experimentation will be required before the specification of practically useful structure-activity relationships are possible.
Journal ArticleDOI
Physiological and toxicological changes in the skin resulting from the action and interaction of metal ions
TL;DR: Evidence presented shows that the balance of trace metal ions is critical for normal skin and repair mechanisms following injury, and xenobiotic ions can impair this balance, leading to pathological change.
Journal ArticleDOI
Human toxicity of cobalt-containing dust and experimental studies on the mechanism of interstitial lung disease (hard metal disease).
TL;DR: Clinical and epidemiological data indicate that this manifestation is rarely, if ever, induced by pure cobalt metal dust alone, but requires the concomitant inhalation of other compounds such as tungsten carbide in the hard metal industry (hard metal disease).
References
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Journal Article
Improved method for the determination of blood glutathione.
Ernest Beutler,O Duron,B M Kelly +2 more
Journal ArticleDOI
Photodermatitis due to tetrachlorsalicylanilide.
TL;DR: Summer of 1960 was not notable for its sunshine and cases of photodermatitis were uncommon, at any rate in Buckinghamshire, but two cases seen in September drew attention to the problem of unexplained light sensitivity, which stimulated an interest into possible causes, including airborne sensitizing pollens.
Journal ArticleDOI
Contact photodermatitis from bithionol.
TL;DR: Patients with contact photodermatitis from bithionol fall into two groups: (a) Transient contact reactors with normal MED and (b) "Persistent light reactors" with lowered MED and positive WGT.
Journal ArticleDOI
Contact allergic sensitivity to plants and the photosensitivity dermatitis and actinic reticuloid syndrome
W. Frain‐Bell,B.E. Johnson +1 more
TL;DR: Contact allergic sensitivity to oleoresin extract from Compositae plants was found to be usually present in individuals suffering from the photosensitivity dermatitis and actinic reticuloid syndrome.
Journal ArticleDOI
The syndrome of chronic photosensitivity dermatitis and actinic reticuloid.
TL;DR: In a Study of thirty‐four male subjects suffering from the syndrome of chronic photosensitivity dermatitis and actinic reticuloid the clinical, histological and photobiological features were such as to suggest that they were in fact examples of a single entity in which the degree of response to ultraviolet and visible light varied.