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Journal ArticleDOI

Photosensitizers of the porphyrin and phthalocyanine series for photodynamic therapy

Raymond Bonnett
- 01 Jan 1995 - 
- Vol. 24, Iss: 1, pp 19-33
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This article is published in Chemical Society Reviews.The article was published on 1995-01-01. It has received 1830 citations till now. The article focuses on the topics: Porphyrin & Phthalocyanine.

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Citations
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An overview of semiconductor photocatalysis

TL;DR: An overview of the field of semiconductor photocatalysis can be found in this paper, where a brief examination of its roots, achievements and possible future is presented, and the semiconductor titanium dioxide (TiO 2 ) features predominantly in past and present work.
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Plasmonic photothermal therapy (PPTT) using gold nanoparticles

TL;DR: The development of the PPTT method is discussed with special emphasis on the recent in vitro and in vivo success using gold nanospheres coupled with visible lasers and gold nanorods and silica–gold nanoshells coupled with near-infrared lasers.
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Multiphoton Absorbing Materials : Molecular Designs, Characterizations, and Applications

TL;DR: Nonlinear Optical Characterizations of Multiphoton Active Materials 1282 5.2.1.
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Reactive oxygen species generating systems meeting challenges of photodynamic cancer therapy

TL;DR: The current status and possible opportunities for ROS generation for cancer therapy are summarized and it is hoped this review will spur pre-clinical research and clinical practice for ROS-mediated tumour treatments.
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Photodynamic antimicrobial chemotherapy (PACT).

TL;DR: Photodynamic antimicrobial chemotherapy (PACT), which predates the related cancer regimen, is proposed as a potential, low-cost approach to the treatment of locally occurring infection.
References
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Journal ArticleDOI

Endogenous protoporphyrin IX, a clinically useful photosensitizer for photodynamic therapy.

TL;DR: Preclinical studies in experimental animals and human volunteers indicate that ALA can induce a localized tissue-specific photosensitization if administered by intradermal injection, opening the possibility of using ALA-induced PpIX to treat tumors that are too thick or that lie too deep to be accessible to either topical or locally injected ALA.
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Photosensitizers: therapy and detection of malignant tumors

TL;DR: Perhaps the most significant advance during the past year has been the initiation of Phase III clinical trials of PDT vs standard therapy in treatment of superficial bladder cancer and obstructive endobronchial tumors.
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Hydroporphyrins of the meso-tetra(hydroxyphenyl)porphyrin series as tumour photosensitizers

TL;DR: Four new hydroporphyrins related to the tetra(hydroxyphenyl)porphyrins show the expected strong absorption bands in the red region of the visible spectrum and are found to be very effective tumour photosensitizers.
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Oral versus intravenous administration of 5-aminolaevulinic acid for photodynamic therapy

TL;DR: The porphyrin sensitisation kinetics profile in the stomach, colon and bladder in normal rats following enterally and parenterally administered ALA was studied using microscopic fluorescence photometric studies of frozen tissue sections and the highest level of fluorescence was achieved in the gastric mucosa and in decreasing levels, colonic and bladder mucosa.