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Physical activity is the strongest predictor of all-cause mortality in patients with COPD: a prospective cohort study.

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TLDR
In this paper, the authors determined the prognostic value of objectively measured physical activity in comparison with established predictors of mortality and evaluated the prognosis value of noninvasive assessments of cardiovascular status, biomarkers of systemic inflammation, and adipokines.
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This article is published in Chest.The article was published on 2011-08-01. It has received 733 citations till now. The article focuses on the topics: Prospective cohort study & Cohort.

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Osteoporosis in Lung Transplantation Candidates: Association With 6-minute Walking Test and Body Mass Index

TL;DR: This is the first study to demonstrate that 6-minute walking distance and bone mineral density independently predict osteoporosis in lung transplant candidates.
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Skeletal muscle is associated with exercise tolerance evaluated by cardiopulmonary exercise testing in Japanese patients with chronic obstructive pulmonary disease.

TL;DR: In this article, the authors investigated the correlation between exercise tolerance and clinical parameters, focusing especially on the cross-sectional area (CSA) of skeletal muscle, and found that PMCSA was weakly correlated after adjustment.
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This patient is not breathing properly: is this COPD, heart failure, or neither?

TL;DR: The diagnostic challenges in distinguishing COPD from HF are highlighted and the implications of their overlap are explored, and the use of biomarkers and treatments for HF in patients with COPD to improve long-term outcomes are explored.
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The Importance of Appropriate Diagnosis in the Practical Management of Chronic Obstructive Pulmonary Disease.

TL;DR: In this paper, the authors provide a current understanding of the importance of an appropriate diagnosis in the real-world management of COPD, which is based on the Global Initiative for Chronic Obstructive Lung Disease (GOLD), the American Thoracic Society (ATS), the European Respiratory Society (ERS), and the Japanese Rheumatology Society (JRS).
References
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Lung volumes and forced ventilatory flows

TL;DR: Assessing the total lung capacity is indispensable in establishing a restrictive ventilatory defect or in diagnosing abnormal lung distensibility, as may occur in patients …
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The Body-Mass Index, Airflow Obstruction, Dyspnea, and Exercise Capacity Index in Chronic Obstructive Pulmonary Disease

TL;DR: The BODE index, a simple multidimensional grading system, is better than the FEV1 at predicting the risk of death from any cause and from respiratory causes among patients with COPD.
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Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease.

TL;DR: The reduction in death from all causes among patients with COPD in the combination-therapy group did not reach the predetermined level of statistical significance, and there were significant benefits in all other outcomes among these patients.
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