Journal ArticleDOI
Physical activity is the strongest predictor of all-cause mortality in patients with COPD: a prospective cohort study.
Benjamin Waschki,Anne Kirsten,Olaf Holz,Kai-Christian Müller,Thorsten Meyer,Henrik Watz,Helgo Magnussen +6 more
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In this paper, the authors determined the prognostic value of objectively measured physical activity in comparison with established predictors of mortality and evaluated the prognosis value of noninvasive assessments of cardiovascular status, biomarkers of systemic inflammation, and adipokines.About:
This article is published in Chest.The article was published on 2011-08-01. It has received 733 citations till now. The article focuses on the topics: Prospective cohort study & Cohort.read more
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Three-year follow-up of Interleukin 6 and C-reactive protein in chronic obstructive pulmonary disease.
TL;DR: The systemic inflammatory process, evaluated by IL-6, seems to be persistent, progressive and associated with mortality and worse physical performance in COPD patients.
Journal ArticleDOI
Sedentary Behavior Is an Independent Predictor of Mortality in Subjects With COPD
Karina Couto Furlanetto,Leila Donária,Lorena Paltanin Schneider,Jose R. Lopes,Marcos Ribeiro,Karen Barros Parron Fernandes,Nidia A. Hernandes,Fabio Pitta +7 more
TL;DR: Sedentary behavior was an independent predictor of mortality in subjects with COPD, even adjusting for moderate-to-vigorous physical activity and a number of other variables, and may open room for future studies aiming at decreasing sedentary time as a promising strategy to reduce mortality risk.
Journal ArticleDOI
Advances in the Evaluation of Respiratory Pathophysiology during Exercise in Chronic Lung Diseases.
Denis E. O'Donnell,Amany F. Elbehairy,Amany F. Elbehairy,Danilo C. Berton,Nicolle J. Domnik,J. Alberto Neder +5 more
TL;DR: This novel approach to CPET interpretation, which includes a quantification of activity-related dyspnea and evaluation of its underlying mechanisms, enhances the ability to meaningfully intervene to improve quality of life in these pathologically-distinct conditions.
Journal ArticleDOI
Prognostic models for outcome prediction in patients with chronic obstructive pulmonary disease: systematic review and critical appraisal
Vanesa Bellou,Lazaros Belbasis,Athanasios Konstantinidis,Ioanna Tzoulaki,Ioanna Tzoulaki,Evangelos Evangelou,Evangelos Evangelou +6 more
TL;DR: A detailed mapping and assessment of the prognostic models for outcome prediction in COPD patients indicates several methodological pitfalls in their development and a low rate of external validation.
Journal ArticleDOI
Cardiopulmonary exercise testing, prehabilitation, and Enhanced Recovery After Surgery (ERAS)
TL;DR: The current and future role of cardiopulmonary exercise testing (CPET) in the context of Enhanced Recovery After Surgery (ERAS) programs is evaluated to suggest that CPET-derived variables can be used to guide the prescription of exercise training interventions and thereby improve physical fitness in patients prior to surgery.
References
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Journal ArticleDOI
Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary.
Jørgen Vestbo,Suzanne S. Hurd,Alvar Agusti,Paul W. Jones,Claus Vogelmeier,Antonio Anzueto,Peter J. Barnes,Leonardo M. Fabbri,Fernando J. Martinez,Masaharu Nishimura,Robert A. Stockley,Don D. Sin,Roberto Rodriguez-Roisin +12 more
TL;DR: It is recommended that spirometry is required for the clinical diagnosis of COPD to avoid misdiagnosis and to ensure proper evaluation of severity of airflow limitation.
Journal ArticleDOI
Lung volumes and forced ventilatory flows
TL;DR: Assessing the total lung capacity is indispensable in establishing a restrictive ventilatory defect or in diagnosing abnormal lung distensibility, as may occur in patients …
Journal Article
Lung volumes and forced ventilatory flows. Report Working Party Standardization of Lung Function Tests, European Community for Steel and Coal. Official Statement of the European Respiratory Society.
Journal ArticleDOI
The Body-Mass Index, Airflow Obstruction, Dyspnea, and Exercise Capacity Index in Chronic Obstructive Pulmonary Disease
Bartolome R. Celli,Claudia Cote,Jose M. Marin,Ciro Casanova,Maria Montes de Oca,Reina A. Mendez,Victor Pinto Plata,Howard Cabral +7 more
TL;DR: The BODE index, a simple multidimensional grading system, is better than the FEV1 at predicting the risk of death from any cause and from respiratory causes among patients with COPD.
Journal ArticleDOI
Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease.
Julie A. Anderson,Bartolome R. Celli,Gary T. Ferguson,Christine Jenkins,Paul W. Jones,Julie C. Yates,Jørgen Vestbo +6 more
TL;DR: The reduction in death from all causes among patients with COPD in the combination-therapy group did not reach the predetermined level of statistical significance, and there were significant benefits in all other outcomes among these patients.
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