Journal ArticleDOI
Place Cells, Grid Cells, and the Brain's Spatial Representation System
TLDR
How place cells and grid cells may form the basis for quantitative spatiotemporal representation of places, routes, and associated experiences during behavior and in memory is reviewed.Abstract:
More than three decades of research have demonstrated a role for hippocampal place cells in representation of the spatial environment in the brain. New studies have shown that place cells are part of a broader circuit for dynamic representation of self-location. A key component of this network is the entorhinal grid cells, which, by virtue of their tessellating firing fields, may provide the elements of a path integration-based neural map. Here we review how place cells and grid cells may form the basis for quantitative spatiotemporal representation of places, routes, and associated experiences during behavior and in memory. Because these cell types have some of the most conspicuous behavioral correlates among neurons in nonsensory cortical systems, and because their spatial firing structure reflects computations internally in the system, studies of entorhinal-hippocampal representations may offer considerable insight into general principles of cortical network dynamics.read more
Citations
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Journal ArticleDOI
Building machines that learn and think like people.
TL;DR: In this article, a review of recent progress in cognitive science suggests that truly human-like learning and thinking machines will have to reach beyond current engineering trends in both what they learn and how they learn it.
Journal ArticleDOI
Neurophysiological and Computational Principles of Cortical Rhythms in Cognition
TL;DR: A plethora of studies will be reviewed on the involvement of long-distance neuronal coherence in cognitive functions such as multisensory integration, working memory, and selective attention, and implications of abnormal neural synchronization are discussed as they relate to mental disorders like schizophrenia and autism.
Journal Article
Multimodal fast optical interrogation of neural circuitry
Feng Zhang,Liping Wang,Martin Brauner,Jana F. Liewald,Kenneth Kay,Natalie Watzke,Phillip G. Wood,Ernst Bamberg,Georg Nagel,Alexander Gottschalk,Karl Deisseroth +10 more
TL;DR: In this paper, an archaeal light-driven chloride pump (NpHR) was developed for temporally precise optical inhibition of neural activity, allowing either knockout of single action potentials, or sustained blockade of spiking.
Journal ArticleDOI
Why Do Humans Reason? Arguments for an Argumentative Theory
Hugo Mercier,Dan Sperber +1 more
TL;DR: The hypothesis is that the function of reasoning is argumentative: It is to devise and evaluate arguments intended to persuade and is adaptive given the exceptional dependence of humans on communication and their vulnerability to misinformation.
Journal ArticleDOI
Memory, navigation and theta rhythm in the hippocampal-entorhinal system
György Buzsáki,Edvard I. Moser +1 more
TL;DR: It is proposed that mechanisms of memory and planning have evolved from mechanisms of navigation in the physical world and hypothesize that the neuronal algorithms underlying navigation in real and mental space are fundamentally the same.
References
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Journal ArticleDOI
Neural networks and physical systems with emergent collective computational abilities
TL;DR: A model of a system having a large number of simple equivalent components, based on aspects of neurobiology but readily adapted to integrated circuits, produces a content-addressable memory which correctly yields an entire memory from any subpart of sufficient size.
Book
The Hippocampus as a Cognitive Map
John O'Keefe,Lynn Nadel +1 more
TL;DR: The amnesic syndrome is presented as an extension of the theory to humans and the role of operators in the locale system is examined.
Journal ArticleDOI
Loss of recent memory after bilateral hippocampal lesions.
TL;DR: The results of these studies point to the importance of the hippocampal complex for normal memory function in patients who had undergone similar, but less radical, bilateral medial temporallobe resections, and as a warning to others of the risk to memory involved in bilateral surgical lesions of the hippocampusal region.
Journal ArticleDOI
Cognitive maps in rats and men
TL;DR: Most of the rat investigations, which I shall report, were carried out in the Berkeley laboratory, and a few, though a very few, were even carried out by me myself.