Journal ArticleDOI
Polycaprolactone-based biomaterials for tissue engineering and drug delivery: Current scenario and challenges
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TLDR
The authors provide an insight into the recent developments and challenges of PCL-based biomaterials as a critical component of new therapeutic strategies for many diseases.Abstract:
Recently, poly (є-caprolactone) (PCL) has gained a lot of attention, and shown great potential in biomedical applications. Among synthetic polymers, PCL is one of the easiest to process and manipulate into a large range of shapes and sizes due to its low melting temperature and its superior viscoelastic properties. In this review article the authors focus mainly on the properties of PCL-based biomaterials relevant to drug delivery and tissue engineering applications. The authors provide an insight into the recent developments and challenges of PCL-based biomaterials as a critical component of new therapeutic strategies for many diseases.read more
Citations
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PCL and PCL-based materials in biomedical applications
TL;DR: PCL is a polyester that has been widely used in tissue engineering field for its availability, relatively inexpensive price and suitability for modification, and it can be used under harsh mechanical, physical and chemical conditions without significant loss of its properties.
Journal ArticleDOI
Polycaprolactone as biomaterial for bone scaffolds: Review of literature
Ruby Dwivedi,Sumit Kumar,Rahul Pandey,Aman Mahajan,Deepti Nandana,Dhirendra S. Katti,Divya Mehrotra +6 more
TL;DR: This review aims to critically analyse the efficacy of PCL as a biomaterial for bone scaffolds to an appreciable level due to its easy availability, cost efficacy and suitability for modification.
Journal ArticleDOI
A Comparative Review of Natural and Synthetic Biopolymer Composite Scaffolds.
M. Sai Bhargava Reddy,Deepalekshmi Ponnamma,Rajan Choudhary,Rajan Choudhary,Kishor Kumar Sadasivuni +4 more
TL;DR: An overview of various natural and synthetic polymers and their possible composite scaffolds with their physicochemical properties including biocompatibility, biodegradability, morphology, mechanical strength, pore size, and porosity are discussed in this article.
Journal ArticleDOI
PCL-Based Composite Scaffold Matrices for Tissue Engineering Applications
TL;DR: This narrative review on polycaprolactone (PCL) affords an insight into the properties and applications of PCL in various tissue engineering applications.
Journal ArticleDOI
A roadmap towards green packaging: The current status and future outlook for polyesters in the packaging industry
TL;DR: In this paper, the authors argue that renewable polyesters can provide a key milestone as renewable plastics in the route toward green packaging and describe different classes of polyesters with particular regard to their potential use as packaging materials.
References
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Scaffolds in tissue engineering bone and cartilage.
TL;DR: Research on the tissue engineering of bone and cartilage from the polymeric scaffold point of view is reviews from a biodegradable and bioresorbable perspective.
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Biodegradable polymers as biomaterials
TL;DR: This review summarizes the main advances published over the last 15 years, outlining the synthesis, biodegradability and biomedical applications ofBiodegradable synthetic and natural polymers.
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Biodegradable synthetic polymers for tissue engineering
TL;DR: Biodegradable synthetic polymers have received recent attention for development of degradable polymers because of their great potential in tailoring polymer structure to achieve mechanical properties and biodegradability to suit a variety of applications.
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Synthesis of polycaprolactone: a review
Marianne Labet,Wim Thielemans +1 more
TL;DR: This critical review summarises the different conditions which have been described to synthesise PCL, and gives a broad overview of the different catalytic systems that were used (enzymatic, organic and metal catalyst systems).
Journal ArticleDOI
Chemical syntheses of biodegradable polymers
TL;DR: Recent advances in chemical syntheses of biodegradable polymers from the standpoint of molecular design are reviewed, with emphasis on controlled synthesis, and their biodegradation is discussed in relation to the molecular structure.