Postmastectomy intensity modulation radiated therapy of chest wall and regional nodes: Retrospective analysis of the performance and complications up for 5 years.
TLDR
Postmastectomy treatment with the IMRT technique can reduce the incidence rate of radiation toxicity by decreasing organs at risk (OARs) irradiation and neoadjuvant chemotherapy and hypertension were the most significant risk factors for acute skin dermatitis and acute radiation induced lung injury.About:
This article is published in Medicine.The article was published on 2017-09-01 and is currently open access. It has received 15 citations till now. The article focuses on the topics: Lung injury & Radiation therapy.read more
Citations
More filters
Journal ArticleDOI
Clinical Effectiveness of an Adaptive Treatment Planning Algorithm for Intensity Modulated Radiation Therapy Versus 3D Conformal Radiation Therapy for Node-Positive Breast Cancer Patients Undergoing Regional Nodal Irradiation/Postmastectomy Radiation Therapy.
Jose G. Bazan,E. Healy,Sasha Beyer,Karla Kuhn,Dominic DiCostanzo,T.L. Smith,Sachin R. Jhawar,Julia White +7 more
TL;DR: An adaptive-TPA for use of IMRT when 3D CRT does not meet critical OAR constraints resulted in rare high-grade toxicity and no difference in failure patterns between patients treated with IMRT and 3DCRT, and should provide reassurance that IMRT maintains the therapeutic ratio by preserving cancer control outcomes without excess toxicity when 3dCRT fails to meet OAR constraint.
Journal ArticleDOI
Dosimetric parameters associated with radiation-induced esophagitis in breast cancer patients undergoing regional nodal irradiation.
Alexander Yaney,Ahmet S. Ayan,Xueliang Pan,Sachin R. Jhawar,E. Healy,Sasha Beyer,Kylee Lindsey,Karla Kuhn,Kayla Tedrick,Julia White,Jose G. Bazan +10 more
TL;DR: In patients receiving RNI with modern techniques, it is found that G2E occurs in >15%, and more frequently with IMRT, and these data strongly support the routine contouring of the esophagus in RNI planning and should be incorporated in future prospective protocols of RNI.
Journal ArticleDOI
Radiation-induced oesophagitis in breast cancer: Factors influencing onset and severity for patients receiving supraclavicular nodal irradiation.
Katrina West,Michal Schneider,Caroline Wright,Rachael Beldham-Collins,Natalie Coburn,Ken W. Tiver,Val Gebski,Kirsty Stuart +7 more
TL;DR: The aim of this study was to determine dosimetric factors, such as mean dose and oesophageal length, which may influence the incidence and severity of Oesophagitis in breast cancer patients receiving radiotherapy to the supraclavicular nodes.
Journal ArticleDOI
The incidence of postoperative radiotherapy-induced acute dermatitis in breast cancer and its influencing factors for Chinese women.
TL;DR: Skin acute reaction in postoperative radiotherapy breast cancer patients is generally common but mild, and there are quite a few patients who need interruption or cessation of the radiotherapy process, especially for the breast-conserving patients.
Journal ArticleDOI
Correlation between toxicity and dosimetric parameters for adjuvant intensity modulated radiation therapy of breast cancer: a prospective study.
David Pasquier,Benoit Bataille,Florence Le Tinier,Raoudha Bennadji,Hélène Langin,A. Escande,Emmanuelle Tresch,F. Darloy,Damien Carlier,F. Crop,Eric Lartigau +10 more
TL;DR: In this paper, a prospective, observational, single-center study of the safety of adjuvant intensity-modulated radiation therapy (IMRT) was extended to a second investigating center.
References
More filters
Journal ArticleDOI
Cancer statistics, 2015.
TL;DR: The overall cancer death rate decreased from 215.1 (per 100,000 population) in 1991 to 168.7 in 2011, a total relative decline of 22%.
Journal ArticleDOI
Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomised trials.
Mike Clarke,Rory Collins,Sarah C. Darby,C Davies,P. Elphinstone,V Evans,J Godwin,Richard Gray,C. Hicks,Spencer L. James,E MacKinnon,Paul McGale,T McHugh,Richard Peto,Carolyn W. Taylor,Yaochen Wang +15 more
TL;DR: It is found that variations in local treatment that substantially affect the risk of locoregional recurrence could also affect long-term breast cancer mortality, and that avoidance of a local recurrence in the conserved breast is recommended.
Journal ArticleDOI
Effect of radiotherapy after mastectomy and axillary surgery on 10-year recurrence and 20-year breast cancer mortality: meta-analysis of individual patient data for 8135 women in 22 randomised trials
Paul McGale,Carolyn W. Taylor,C Correa,D Cutter,F Duane,Marianne Ewertz,Richard Gray,Gurdeep S. Mannu,Richard Peto,Timothy J. Whelan,Yixin Wang,Zhe Wang,Sarah C. Darby +12 more
TL;DR: After mastectomy and axillary dissection, radiotherapy reduced both recurrence and breast cancer mortality in the women with one to three positive lymph nodes in these trials even when systemic therapy was given.
Journal ArticleDOI
Lymphedema secondary to postmastectomy radiation: incidence and risk factors.
Christian S. Hinrichs,Nancy Watroba,Hamed Rezaishiraz,William Giese,Thelma C. Hurd,Kathleen A. Fassl,Stephen B. Edge +6 more
TL;DR: The high incidence and debilitating effects of lymphedema must be weighed against the benefits of PMRT, and efforts to prevent lyMPhedema should be emphasized.
Journal ArticleDOI
Breast Cancer-Related Arm Lymphedema: Incidence Rates, Diagnostic Techniques, Optimal Management and Risk Reduction Strategies
Chirag Shah,Frank A. Vicini +1 more
TL;DR: A review of the latest data addressing all of these concerns in order to provide patients and health care providers with optimal, contemporary recommendations is presented in this article, where a multidisciplinary approach to the management of BCRL should begin prior to definitive treatment for breast cancer employing patient-specific surgical, radiation therapy, and chemotherapy paradigms that limit risks.