Journal ArticleDOI
Practical and Useful Methods for the Enantioselective Reduction of Unsymmetrical Ketones
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TLDR
In this article, the recently developed oxazaborolidine catalyzed reduction along with other useful reagents are discussed and compared with other traditional reagents for the reduction of unsymmetrical ketones to optically active alcohols.Abstract:
Enantioselective reduction of unsymmetrical ketones to optically active alcohols is very important in organic synthesis. Catalytic methods have been developed for this process and have not been reviewed previously. In this article the recently developed oxazaborolidine catalyzed reduction along with other useful reagents will be discussed.read more
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Journal ArticleDOI
1,2-Amino Alcohols and Their Heterocyclic Derivatives as Chiral Auxiliaries in Asymmetric Synthesis
Journal ArticleDOI
Asymmetric syntheses with chiral oxazaborolidines
Sabine Wallbaum,Jürgen Martens +1 more
Journal ArticleDOI
Recent developments in the chemistry of amine- and phosphine-boranes
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The Chemistry of α-Haloketones and Their Utility in Heterocyclic Synthesis
TL;DR: The molecular structures and spectral properties of α-haloketones as well as their syntheses are analyzed and reviewed in this paper, where their reactivity towards oxygen, nitrogen, and sulfur nucleophiles, carboxylic acids, carbon nucleophilic, alkenes, and alkynes are discussed.
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Chiral pyridine N-oxides: Useful ligands for asymmetric catalysis
TL;DR: In this article, the synthesis and applications in asymmetric catalysis of chiral pyridine Noxide derivatives are reviewed and a review of the main applications of chirality is presented.